Skip to main content

NCBI: A Novel Correlation Based Imputing Technique Using Biclustering

  • Conference paper
  • First Online:
Computational Intelligence in Pattern Recognition

Abstract

Presence of missing values (MV) in gene expression data is commonplace. It significantly affects the performance of statistical analysis and machine learning algorithms. Discarding objects or attributes with missing values and inappropriate estimation of MVs lead to high information loss and misleading results. So, it is necessary to have an accurate technique for missing value imputation. In this paper, we present a novel correlation based missing value imputation technique for gene expression datasets. We refer to our method as NCBI. We compare the estimation accuracy of our technique with two widely used methods such as KNNI and KMI, on four benchmark datasets by randomly knocking out data values as missing. Our technique can estimate missing values almost 20–25% more accurately than KNNI and KMI in all datasets.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Ahmed, H.A., Mahanta, P., Bhattacharyya, D.K., Kalita, J.K.: Shifting-and-scaling correlation based biclustering algorithm. IEEE/ACM Trans. Comput. Biol. Bioinform. (TCBB) 11(6), 1239–1252 (2014)

    Article  Google Scholar 

  2. Batista, G.E., Monard, M.C.: An analysis of four missing data treatment methods for supervised learning. Appl. Artif. Intell. 17(5–6), 519–533 (2003)

    Article  Google Scholar 

  3. Benesty, J., Chen, J., Huang, Y., et al.: Pearson correlation coefficient. In: Noise Reduction in Speech Processing, pp. 1–4. Springer (2009)

    Google Scholar 

  4. Bennett, D.A.: How can I deal with missing data in my study? Aust. N. Z. J. Public Health 25(5), 464–469 (2001)

    Article  Google Scholar 

  5. Bø, T.H., Dysvik, B., Jonassen, I.: LSimpute: accurate estimation of missing values in microarray data with least squares methods. Nucl. Acids Res. 32(3), e34–e34 (2004)

    Article  Google Scholar 

  6. Chowdhury, H.A., Bhattacharyya, D.K.: mRMR+: an effective feature selection algorithm for classification. In: International Conference on Pattern Recognition and Machine Intelligence, pp. 424–430. Springer (2017)

    Google Scholar 

  7. Li, D., Deogun, J., Spaulding, W., et al.: Towards missing data imputation: a study of fuzzy k-means clustering method. In: Rough Sets and Current Trends in Computing, pp. 573–579. Springer (2004)

    Google Scholar 

  8. Liew, A.W.C., Law, N.F., Yan, H.: Missing value imputation for gene expression data: computational techniques to recover missing data from available information. Brief. Bioinform. 12(5), 498–513 (2011)

    Article  Google Scholar 

  9. Little, R.J., Rubin, D.B.: Statistical Analysis with Missing Data. Wiley (2014)

    Google Scholar 

  10. Mahanta, P., Ahmed, H.A., Bhattacharyya, D.K., Kalita, J.K.: An effective method for network module extraction from microarray data. BMC Bioinform. 13(13), S4 (2012)

    Article  Google Scholar 

  11. Troyanskaya, O., Cantor, M., Sherlock, G., et al.: Missing value estimation methods for DNA microarrays. Bioinformatics 17(6), 520–525 (2001)

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Dhruba Kumar Bhattacharyya .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Singapore Pte Ltd.

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Chowdhury, H.A., Ahmed, H.A., Bhattacharyya, D.K., Kalita, J.K. (2020). NCBI: A Novel Correlation Based Imputing Technique Using Biclustering. In: Das, A., Nayak, J., Naik, B., Pati, S., Pelusi, D. (eds) Computational Intelligence in Pattern Recognition. Advances in Intelligent Systems and Computing, vol 999. Springer, Singapore. https://doi.org/10.1007/978-981-13-9042-5_43

Download citation

Publish with us

Policies and ethics