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Role of Extracellular Vesicles in Renal Inflammation and Fibrosis

  • Lin-Li LvEmail author
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1165)

Abstract

Extracellular vesicles (EVs) are the membrane-surrounded structures released by almost all types of cells. Accumulating evidences have suggested that EVs secretion is enhanced under stress conditions and have been associated with a large wide of cellular physiological and pathological processes. In this part, recent understanding about the generation and biological function of EVs was reviewed. Moreover, the role of EVs in renal inflammation and fibrosis and future challenges of EVs study in kidney disease were discussed.

Keywords

Extracellular vesicles Renal fibrosis Renal inflammation Biomarker 

Notes

Acknowledgements

This chapter was modified from a paper reported by our group in J Cell Mol Med (Lv et al. 2019).

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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  1. 1.Institute of Nephrology, Zhong Da HospitalSoutheast University School of MedicineNanjingChina

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