Abstract
Drug-resistance in plasmodium parasites is manifested at large scale, putting all the malaria control efforts in vain with an urgent need of complementary strategies. A deeper understanding of mechanism of action of drugs, drug resistance and cross-resistance between drugs will pave a way to design an effective individualized drug for malaria-affected regions. This chapter summarizes the molecular mechanism of all currently available anti-malarial drugs and the factors playing significant role in the development and spread of resistance against the antimalarials.
Keywords
Authors Juveria Khan and Monika Kaushik have equally contributed to this chapter.
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Khan, J., Kaushik, M., Singh, S. (2019). Molecular Mechanisms of Action and Resistance of Antimalarial Drugs. In: Mandal, S., Paul, D. (eds) Bacterial Adaptation to Co-resistance. Springer, Singapore. https://doi.org/10.1007/978-981-13-8503-2_14
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