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Microbial Diversity in Ecosystem Sustainability and Biotechnological Applications pp 23–47Cite as

Bioinformatics Tools for Microbial Diversity Analysis

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Abstract

With several microbes discovered and rediscovered, there is a growing need to understand their lineage, origin, and occurrence. Given the microbial diversity and its importance in global impact, it would be interesting to explore the microbial resources to better disseminate the phenotyping, epidemiological investigations, screening, and metagenomics. There are several bioinformatics tools to mention from phylogenetic taxa, sequence and structural relationship, evolutionary mechanisms, horizontal gene transfer, and importantly functional genomics. Here we bring an overview of genomic tools that have aided identifying isolates, species, and subspecies of uncultured microorganisms and inferring their functional roles. While giving a gist of tools, we also discuss the features and limitations of these tools in the light of the emergence of next-generation sequencing (NGS) technologies.

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Acknowledgments

We gratefully acknowledge the resources provided by Biotechnology Information System (BTIS) - Sub Distributed Information Centre (Sub-DIC), BISR funded by Department of Biotechnology, Government of India. The authors wish to acknowledge the contributions of Mr. Narendra Meena, Ms. Pragya Chaturvedi, and Ms. Sweta Shrotriya in collecting the information and checking the tools. The encouragement provided by Prof. P. Ghosh, Executive Director, BISR is gratefully acknowledged.

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  1. Department of Biotechnology and Bioinformatics, Birla Institute of Scientific Research, Jaipur, Rajasthan, India

    Raghavender Surya Upadhyayula, Pooran Singh Solanki, Prashanth Suravajhala & Krishna Mohan Medicherla

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  1. Raghavender Surya Upadhyayula
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  2. Pooran Singh Solanki
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  3. Prashanth Suravajhala
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Correspondence to Krishna Mohan Medicherla .

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Editors and Affiliations

  1. Division of Biological Sciences & Engineering, Netaji Subhas University of Technology, New Delhi, Delhi, India

    Tulasi Satyanarayana

  2. Department of Biotechnology, Barkatullah University, Bhopal, Madhya Pradesh, India

    Bhavdish Narain Johri

  3. Division of Molecular Microbiology, Institute of Life Sciences, Bhubaneswar, Odisha, India

    Subrata Kumar Das

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Upadhyayula, R.S., Solanki, P.S., Suravajhala, P., Medicherla, K.M. (2019). Bioinformatics Tools for Microbial Diversity Analysis. In: Satyanarayana, T., Johri, B., Das, S. (eds) Microbial Diversity in Ecosystem Sustainability and Biotechnological Applications. Springer, Singapore. https://doi.org/10.1007/978-981-13-8315-1_2

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