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Oxidative Stress in Heart Diseases pp 3–18Cite as

Oxidative Stress and Cardiovascular Risk and Prevention in Children and Adolescents

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Abstract

The process of atherosclerosis may begin early in lifetime and develop for decades, until leading to manifest cardiovascular disease (CVD).

Efforts for early identification and management of predisposing factors for CVD for primordial and primary prevention, sustaining the “ideal cardiovascular health”, must start early in life.

Oxidative stress is among the first signs of endothelial activation and cardiometabolic alterations, and might serve in future as an early tool to predict risk of developing cardiometabolic and lifestyle-related diseases in childhood and adolescence and later in adulthood.

This review aims to discuss available data on all these aspects, with particular emphasis on the relationship between cardiometabolic risk and oxidative stress in children and adolescents.

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Authors and Affiliations

  1. Istituto di Fisiologia Clinica, CNR, Pisa, Italy

    Francesca Mastorci, Laura Sabatino, Alessandro Pingitore, Rudina Ndreu & Cristina Vassalle

  2. Fondazione CNR-Regione Toscana G. Monasterio, Pisa, Italy

    Irene Traghella & Cristina Vassalle

Authors
  1. Francesca Mastorci
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  2. Irene Traghella
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  3. Laura Sabatino
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  4. Alessandro Pingitore
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  5. Rudina Ndreu
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  6. Cristina Vassalle
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Corresponding author

Correspondence to Cristina Vassalle .

Editor information

Editors and Affiliations

  1. Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, West Bengal, India

    Sajal Chakraborti

  2. Institute of Cardiovascular Sciences, St Boniface Hospital, Albrechtsen Research Centre, Winnipeg, MB, Canada

    Naranjan S Dhalla

  3. Translational Health Science and Technology (THSTI), Department of Biotechnology, Faridabad, India

    Nirmal K Ganguly

  4. Translational Health Science and Technology (THSTI), Department of Biotechnology, Faridabad, India

    Madhu Dikshit

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Mastorci, F., Traghella, I., Sabatino, L., Pingitore, A., Ndreu, R., Vassalle, C. (2019). Oxidative Stress and Cardiovascular Risk and Prevention in Children and Adolescents. In: Chakraborti, S., Dhalla, N., Ganguly, N., Dikshit, M. (eds) Oxidative Stress in Heart Diseases. Springer, Singapore. https://doi.org/10.1007/978-981-13-8273-4_1

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