Intracranial and Intraocular Pressure-Related Diseases

  • Diya Yang
  • Ningli WangEmail author
  • Yunxiao Sun
Part of the Advances in Visual Science and Eye Diseases book series (AVSED, volume 3)


The retinal ganglion cells in the closed eyeball converge into the optic nerve, which passes out the eye through the lamina cribrosa, and is surrounded by the three layers of meningeal tissues which communicate with cerebrospinal fluid system of brain, and then projects on the lateral geniculate body—this is the visual way of anatomical knowledge what we are familiar with, which is well learned by all surgeons of ophthalmology, neurology, and head and neck; however, for a long time, experts in different area kept on just focusing on diseases of their own specialized subjects, digging in some research directions more sophisticated but narrow, while ignoring the necessity of integration underlying the basis of anatomy. Analyzing with the thinking pattern of integrative ophthalmology (IO) and mainly directed by the pressure correlation between the two closed chambers, this text puts forward the new concept of “intracranial and intraocular pressure-related diseases” based on the anatomical basis; introduces the primary epidemiology characteristics of the intracranial and intraocular pressure-related diseases; discusses the clinical characteristics and current research of the damage to the optical nerve due to the intraocular pressure (ICP) and the intracranial pressure (IOP) difference increase, including situations as IOP > ICP and ICP > IOP; and lists the possible mechanism of disorders of communication between intracranial and intraocular cavities such as Terson syndrome and eyes with silicone oil tamponade, high myopia, and so on. Starting from this text, hopefully readers might reflect on eye diseases from the perspective of IO, break down the boundaries of different disciplines and departments, and make the diseases having eye syndromes get more comprehensive understanding.

Copyright information

© Springer Nature Singapore Pte Ltd. and People's Medical Publishing House, PR of China 2020

Authors and Affiliations

  1. 1.Beijing Tongren Eye Center; Beijing Tongren HospitalCapital Medical UniversityBeijingChina
  2. 2.Beijing Ophthalmology and Visual Sciences Key LaboratoryBeijingChina
  3. 3.Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren HosptialCapital Medical UniversityBeijingChina

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