Abstract
Bacteriocin is a kind of antibiotic substance produced by bacteria in the metabolic process and has the function of resisting bacteria, fungi, or viruses. The intrinsic nature of bacteriocin is protein or polypeptide. For producing strain, bacteriocin is a biological weapon as it can inhibit or kill competitors in complex or harsh environments.
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References
Abbasiliasi S et al (2011) Effect of medium composition and culture condition on the production of bacteriocin-like inhibitory substances (blis) by lactobacillus paracasei la07, a strain isolated from BUDU. Biotechnol Biotechnol Equip 25(4):2652–2657
Anand SK, Srinivasan RA, Rao LK (1984) Antibacterial activity associated with Bifidobacterium bifidum. Cult Dairy Prod J 19:6–8
Anderssen EL et al (1998) Antagonistic activity of lactobacillus plantarum C11: two new two-peptide bacteriocins, plantaricins EF and JK, and the induction factor plantaricin a. Appl Environ Microb 64(6):2269–2272
Arakawa K et al (2009a) Effects of gassericins a and T, bacteriocins produced by lactobacillus gasseri, with glycine on custard cream preservation. J Dairy Sci 92(6):2365–2372
Arakawa K et al (2009b) Negative effect of divalent metal cations on production of gassericin T, a bacteriocin produced by lactobacillus gasseri, in milk-based media. Int Dairy J 19(10):612–616
Aunpad R, Na-Bangchang K (2007) Pumilicin 4, a novel bacteriocin with anti-MRSA and anti-VRE activity produced by newly isolated bacteria Bacillus pumilus strain WAPB4. Curr Microbiol 55(4):308–313
Aymerich T et al (1996) Biochemical and genetic characterization of enterocin a from Enterococcus faecium, a new antilisterial bacteriocin in the pediocin family of bacteriocins. Appl Environ Microbiol 62(5):1676–1682
Bhunia AK et al (1991) Mode of action of pediocin AcH from Pediococcus acidilactici H on sensitive bacterial strains. J Appl Bacteriol 70(1):25–33
Brotz H et al (1997) The lantibiotic mersacidin inhibits peptidoglycan biosynthesis at the level of transglycosylation. Eur J Biochem 246(1):193–199
Casaus P et al (1997) Enterocin B, a new bacteriocin from Enterococcus faecium T136 which can act synergistically with enterocin a. Microbiology-Uk 143:2287–2294
Chatterjee S et al (1992) Mersacidin, a new antibiotic from Bacillus fermentation, isolation, purification and chemical characterization. J Antibiot 45(6):832–838
Cheikhyoussef A et al (2010) Bifidin I–A new bacteriocin produced by Bifidobacterium infantis BCRC 14602: purification and partial amino acid sequence. Food Control 21(5):746–753
Cintas LM et al (2000) Biochemical and genetic evidence that Enterococcus faecium L50 produces enterocins L50A and L50B, the sec-dependent enterocin P, and a novel bacteriocin secreted without an N-terminal extension termed enterocin Q. J Bacteriol 182(23):6806–6814
Collado MC, Hernandez M, Sanz Y (2005a) Production of bacteriocin-like inhibitory compounds by human fecal Bifidobacterium strains. J Food Prot 68(5):1034–1040
Collado MC et al (2005b) Antimicrobial peptides are among the antagonistic metabolites produced by Bifidobacterium against helicobacter pylori. Int J Antimicrob Agents 25(5):385–391
Cotter PD, Hill C, Ross RP (2005) Bacteriocins: developing innate immunity for food. Nat Rev Microbiol 3(10):777–788
Davies EA, Bevis HE, Delves–Broughton J (1997) The use of the bacteriocin, nisin, as a preservative in ricotta–type cheeses to control the food–borne pathogen Listeria monocytogenes. Lett Appl Microbiol 24(5):343–346
de Arauz LJ et al (2012) Culture medium of diluted skimmed milk for the production of nisin in batch cultivations. Ann Microbiol 62(1):419–426
de Kwaadsteniet M, ten Doeschate K, Dicks LMT (2008) Characterization of the structural gene encoding Nisin F, a new lantibiotic produced by a Lactococcus lactis subsp lactis isolate from freshwater catfish (Clarias gariepinus). Appl Environ Microbiol 74(2):547–549
Diep DB et al (1994) The gene encoding plantaricin a, a bacteriocin from lactobacillus plantarum C11, is located on the same transcription unit as an agr-like regulatory system. Appl Environ Microbiol 60(1):160–166
Dobson AE, Sanozky-Dawes RB, Klaenhammer TR (2007) Identification of an operon and inducing peptide involved in the production of lactacin B by lactobacillus acidophilus. J Appl Microbiol 103(5):1766–1778
Draper LA et al (2013) The two peptide lantibiotic lacticin 3147 acts synergistically with polymyxin to inhibit gram negative bacteria. BMC Microbiol 13(1):1–8
Eijsink VGH et al (1998) Comparative studies of class IIa bacteriocins of lactic acid bacteria. Appl Environ Microbiol 64(9):3275–3281
Espeche MC et al (2014) Physicochemical factors differentially affect the biomass and bacteriocin production by bovine Enterococcus mundtii CRL1656. J Dairy Sci 97(2):789–797
Etchells JL et al (1964) Pure culture fermentation of brined cucumbers. Appl Microbiol 12(6):523–535
Fimland G et al (2005) Pediocin-like antimicrobial peptides (class IIa bacteriocins) and their immunity proteins: biosynthesis, structure, and mode of action. J Pept Sci 11(11):688–696
Flynn S et al (2002) Characterization of the genetic locus responsible for the production of ABP-118, a novel bacteriocin produced by the probiotic bacterium lactobacillus salivarius subsp salivarius UCC118. Microbiology-Sgm 148:973–984
Garneau S, Martin NI, Vederas JC (2002) Two-peptide bacteriocins produced by lactic acid bacteria. Biochimie 84(5-6):577–592
Gross E, Morell JL (1971) Structure of nisin. J Am Chem Soc 93(18):4634–4635
Hastings JW, Sailer M, Johnson K, Roy KL, Vederas JC, Stiles ME (1991) Characterization of Leucocin A-UAL 187 and cloning of the Bacteriocin Cene from Leuconostoc gelidum. J Bacteriol 173(23):7491–7501
Havarstein LS, Holo H, Nes IF (1994) The leader peptide of colicin V shares consensus sequences with leader peptides that are common among peptide bacteriocins produced by gram-positive bacteria. Microbiology-Uk 140:2383–2389
Heinrich P et al (1987) The molecular organization of the lysostaphin gene and its sequences repeated in tandem. Mol Gen Genet MGG 209(3):563–569
Hindre T et al (2004) Regulation of lantibiotic lacticin 481 production at the transcriptional level by acid pH. FEMS Microbiol Lett 231(2):291–298
Hoover DG, Steenson LR (2014) Bacteriocins of lactic acid bacteria. Academic Press, New York
Hui FM, Zhou LX, Morrison DA (1995) Competence for genetic transformation in Streptococcus pneumoniae: organization of a regulatory locus with homology to two lactococcin a secretion genes. Gene 153(1):25–31
Huo, G. C. Research and application of lactic acid bacteria. 2007
Jia SR (2009) Biological preservatives. China Light Industry Press, Beijing
Joerger MC, Klaenhammer TR (1986) Characterization and purification of helveticin J and evidence for a chromosomally determined bacteriocin produced by lactobacillus helveticus 481. J Bacteriol 167(2):439–446
Kawai Y et al (2009) DNA sequencing and homologous expression of a small peptide conferring immunity to Gassericin a, a circular Bacteriocin produced by lactobacillus gasseri LA39. Appl Environ Microbiol 75(5):1324–1330
King BF, Biel ML, Wilkinson BJ (1980) Facile penetration of the Staphylococcus aureus capsule by lysostaphin. Infect Immun 29(3):892–896
Klaenhammer TR (1993) Genetics of bacteriocins produced by lactic acid bacteria. FEMS Microbiol Rev 12(1-3):39–85
Konisky J (1982) Colicins and other bacteriocins with established modes of action. Annu Rev Microbiol 36(1):125–144
Kuipers OP et al (1993) Characterization of the nisin gene cluster nisABTCIPR of Lactococcus lactis. Eur J Biochem 216(1):281–291
Magnusson J, Schnürer J (2001) Lactobacillus coryniformis subsp. coryniformis strain Si3 produces a broad-Spectrum Proteinaceous antifungal compound. Appl Environ Microbiol 67(1):1–5
Maisnierpatin S et al (1992) Inhibition of listeria-monocytogenes in camembert cheese made with a nisin-producing starter. Lait 72(3):249–263
Mandal V, Sen SK, Mandal NC (2010) Assessment of antibacterial activities of pediocin produced by Pediococcus acidilactici lab 5. J Food Saf 30(3):635–651
Mandal V, Sen SK, Mandal NC (2011) Isolation and characterization of pediocin NV 5 producing Pediococcus acidilactici LAB 5 from vacuum-packed fermented meat product. Indian J Microbiol 51(1):22–29
Marciset O et al (1997) Thermophilin 13, a nontypical antilisterial poration complex bacteriocin, that functions without a receptor. J Biol Chem 272(22):14277–14284
Mathiesen G et al (2005) Characterization of a new bacteriocin operon in sakacin P-producing lactobacillus sakei, showing strong translational coupling between the bacteriocin and immunity genes. Appl Environ Microbiol 71(7):3565–3574
Mathys S, Meile L, Lacroix C (2009) Co-cultivation of a bacteriocin-producing mixed culture of Bifidobacterium thermophilum RBL67 and Pediococcus acidilactici UVA1 isolated from baby faeces. J Appl Microbiol 107(1):36–46
Miescher S et al (2000) Propionicin SM1, a bacteriocin from Propionibacterium jensenii DF1: isolation and characterization of the protein and its gene. Syst Appl Microbiol 23(2):174–184
Morgan SM et al (2005) Sequential actions of the two component peptides of the lantibiotic lacticin 3147 explain its antimicrobial activity at nanomolar concentrations. Antimicrob Agents Chemother 49(7):2606–2611
Mortvedt CI et al (1991) Purification and amino-acid-sequence of lactocin-S, a bacteriocin produced by lactobacillus-sake-L45. Appl Environ Microbiol 57(6):1829–1834
Mulders JWM et al (1991) Identification and characterization of the Lantibiotic Nisin-Z, a natural Nisin variant. Eur J Biochem 201(3):581–584
Müller E, Radler F (1993) Caseicin, a bacteriocin from Lactobacillus casei. Folia Microbiol 38(6):441–446
Muriana PM, Klaenhammer TR (1991) Purification and partial characterization of lactacin F, a bacteriocin produced by lactobacillus acidophilus 11088. Appl Environ Microbiol 57(1):114–121
Nakamura K et al (2013) Food preservative potential of gassericin A-containing concentrate prepared from cheese whey culture supernatant of lactobacillus gasseri LA39. Anim Sci J 84(2):144–149
Nes IF et al (1996) Biosynthesis of bacteriocins in lactic acid bacteria. Antonie Van Leeuwenhoek 70(2-4):113–128
Neumann VC et al (1993) Extracellular proteolytic activation of bacteriolytic peptidoglycan hydrolases of Staphylococcus simulans biovar staphylolyticus. FEMS Microbiol Lett 110(2):205–212
Nilsen T, Nes IF, Holo H (2003) Enterolysin a, a cell wall-degrading bacteriocin from Enterococcus faecalis LMG 2333. Appl Environ Microbiol 69(5):2975–2984
Paik SH, Chakicherla A, Hansen JN (1998) Identification and characterization of the structural and transporter genes for, and the chemical and biological properties of, sublancin 168, a novel lantibiotic produced by Bacillus subtilis 168. J Biol Chem 273(36):23134–23142
Parente E, Ricciardi A (1994) Influence of pH on the production of enterocin 1146 during batch fermentation. Lett Appl Microbiol 19(1):12–15
Rayman MK, Aris B, Hurst A (1981) Nisin: a possible alternative or adjunct to nitrite in the preservation of meats. Appl Environ Microbiol 41(2):375–380
Rayman K, Malik N, Hurst A (1983) Failure of nisin to inhibit outgrowth of Clostridium botulinum in a model cured meat system. Appl Environ Microbiol 46(6):1450–1452
Reeves P (2012) The bacteriocins, vol 11. Springer, New York
Riley MA, Chavan MA (2007a) Bacteriocins. Springer, Berlin/Heidelberg
Riley MA, Chavan MA (2007b) Bacteriocins: ecology and evolution. Springer, Berlin/Heidelberg
Rodriguez JM, Martinez MI, Kok J (2002) Pediocin PA-1, a wide-spectrum bacteriocin from lactic acid bacteria. Crit Rev Food Sci Nutr 42(2):91–121
Rueckert PW et al (1979) Mammalian and microbial cell-free conversion of anthracycline antibiotics and analogs. J Antibiot 32(2):141–147
Schneider TR et al (2000) Ab initio structure determination of the lantibiotic mersacidin. Acta Crystallograph Sect D-Biol Crystallograph 56:705–713
Tanner SA et al (2014) Synergistic effects of Bifidobacterium thermophilum RBL67 and selected prebiotics on inhibition of Salmonella colonization in the swine proximal colon PolyFermS model. Gut Pathog 6(1):44
Tolonen M et al (2004) Formation of nisin, plant-derived biomolecules and antimicrobial activity in starter culture fermentations of sauerkraut. Food Microbiol 21(2):167–179
Twomey D et al (2002) Lantibiotics produced by lactic acid bacteria: structure, function and applications. Anton Leeuw Int J Gen Mol Microbiol 82(1-4):165–185
Tyne DV, Martin MJ, Gilmore MS (2013) Structure, function, and biology of the Enterococcus faecalis Cytolysin. Toxins 5(5):895–911
Upreti GC, Hinsdill RD (1975) Production and mode of action of lactocin 27: bacteriocin from a homofermentative lactobacillus. Antimicrob Agents Chemother 7(2):139–145
van den Hooven HW et al (1996) Surface location and orientation of the lantibiotic nisin bound to membrane-mimicking micelles of dodecylphosphocholine and of sodium dodecylsulphate. Eur J Biochem 235(1–2):394–403
Venema K et al (1995) Functional analysis of the pediocin operon of Pediococcus acidilactici PAC1. 0: PedB is the immunity protein and PedD is the precursor processing enzyme. Mol Microbiol 17(3):515–522
Whitford MF et al (2001) Identification of bacteriocin-like inhibitors from rumen Streptococcus spp. and isolation and characterization of bovicin 255. App Environ Microbiol 67(2):569–574
Wirawan RE et al (2006) Molecular and genetic characterization of a novel nisin variant produced by Streptococcus uberis. Appl Environ Microbiol 72(2):1148–1156
Yildirim Z, Johnson MG (1998) Characterization and antimicrobial spectrum of bifidocin B, a bacteriocin produced by Bifidobacterium bifidum NCFB 1454. J Food Prot 61(1):47–51
Yonezawa H, Kuramitsu HK (2005) Genetic analysis of a unique bacteriocin, Smb, produced by Streptococcus mutans GS5. Antimicrob Agents Chemother 49(2):541–548
Zendo T et al (2003) Identification of the lantibiotic Nisin Q, a new natural nisin variant produced by Lactococcus lactis 61-14 isolated from a river in Japan. Biosci Biotechnol Biochem 67(7):1616–1619
Zihler A et al (2011) Protective effect of probiotics on Salmonella infectivity assessed with combined in vitro gut fermentation-cellular models. BMC Microbiol 11:264
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Zhang, Q. (2019). Lactic Acid Bacteria and Bacteriocins. In: Chen, W. (eds) Lactic Acid Bacteria. Springer, Singapore. https://doi.org/10.1007/978-981-13-7283-4_4
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