Malaria, a potentially life-threatening parasitic infection transmitted by mosquitoes, continues to be a major global health problem. Malaria remains the most common cause of fever in returned travellers, with an estimated 10,000 cases of travel-associated malaria occuring globally every year. Young children, pregnant women and asplenic individuals are particularly vulnerable to severe malaria, and malaria acquisition is more common among visiting friends and relatives (VFR) travellers, long-term travellers and expatriates. In this chapter, we discuss the global epidemiology of malaria and preventive measures that can be employed to reduce the risk of malaria acquisition by travellers. We include detail on the drugs available for malaria chemoprophylaxis and the different preventive strategies that can be employed, and we provide advice on how to choose the appropriate strategy and drug for the individual traveller.
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