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The Application of DNA Amplification Strategies in the Field of Photoelectrochemical Biosensor

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Abstract

In this section, the strategy for isothermal amplification of nucleic acids has been applied in photoelectrochemistry. Based on the signal format, the main established strategies for PEC sensor can be classified as steric hindrance, biocatalytic precipitation , in situ generation of electron donor/acceptor, quenching effect, DNA conformational change, introduction of photoelectric active materials, and so on. Herein, we provide a comprehensive overview of the application of DNA amplification in different photoelectrochemical modes. Using illustrative examples, this brief review highlights the current advances in this topic.

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References

  • Arias AC, Mackenzie JD, Mcculloch I et al (2010) Materials and applications for large area electronics: solution-based approaches. Chem Rev 110:3–24

    Article  CAS  Google Scholar 

  • Bettazzi F, Palchetti I (2018) Photoelectrochemical genosensors for the determination of nucleic acid cancer biomarkers. Curr Opin Electrochem 12:51–59

    Article  CAS  Google Scholar 

  • Cha TG, Pan J, Chen HR et al (2015) Design principles of DNA enzyme-based walkers: translocation kinetics and photoregulation. J Am Chem Soc 137:9429–9437

    Article  CAS  Google Scholar 

  • Cheng LY, Zhou J, Zou Q et al (2012) A nanohybrid of graphene oxide–fluorescein derived silyl ether for photocurrent generation triggered by F ions. Rsc Adv 2:4623–4626

    Article  CAS  Google Scholar 

  • Da HM, Liu HY, Zheng YN et al (2018) A highly sensitive VEGF165 photoelectrochemical biosensor fabricated by assembly of aptamer bridged DNA networks. Biosens Bioelectron 101:213–218

    Article  CAS  Google Scholar 

  • Gong LS, Dai H, Zhang SP et al (2016) Silver iodide-chitosan nanotag induced biocatalytic precipitation for self-enhanced ultrasensitive photocathodic immunosensor. Anal Chem 88:5775–5782

    Article  CAS  Google Scholar 

  • Haddour N, Chauvin J, Gondran C et al (2006) Photoelectrochemical immunosensor for label-free detection and quantification of anti-cholera toxin antibody. J Am Chem Soc 128:9693–9698

    Article  CAS  Google Scholar 

  • Hagfeldt A, Boschloo G, Sun LC et al (2010) Dye-sensitized solar cells. Chem Rev 110:6595–6663

    Article  CAS  Google Scholar 

  • Hisatomi T, Kubota J, Domen K (2014) Recent advances in semiconductors for photocatalytic and photoelectrochemical water splitting. Chem Soc Rev 43:7520–7535

    Article  CAS  Google Scholar 

  • Hojeij M, Su B, Tan S et al (2008) Nanoporous photocathode and photoanode made by multilayer assembly of quantum dots. ACS Nano 2:984–992

    Article  CAS  Google Scholar 

  • Huang LJ, Zhang L, Yang L et al (2018a) Manganese porphyrin decorated on DNA networks as quencher and mimicking enzyme for construction of ultrasensitive photoelectrochemistry aptasensor. Biosens Bioelectron 104:21–26

    Article  CAS  Google Scholar 

  • Huang LG, Yang L, Zhu CC et al (2018b) Methylene blue sensitized photoelectrochemical biosensor with 3,4,9,10-perylene tetracarboxylic acidfilm as photoelectric material for highly sensitive Pb2+ detection. Sens Actuators B 274:458–463

    Article  CAS  Google Scholar 

  • Li MJ, Zheng YN, Liang WB et al (2016) An ultrasensitive “on-off-on” photoelectrochemical aptasensor based on signal amplification of a fullerene/CdTe quantum dots sensitized structure and efficient quenching by manganese porphyrin. Chem Commun 52:8138–8141

    Article  CAS  Google Scholar 

  • Li MJ, Zheng YN, Liang WB et al (2017a) Using p-type PbS quantum dots to quench photocurrent of fullerene-AuNP@MoS2 composite structure for ultrasensitive photoelectrochemical detection of ATP. ACS Appl Mater Interfaces 9:42111–4212

    Article  CAS  Google Scholar 

  • Li CX, Lu WS, Zhu M et al (2017b) Development of visible-light induced photoelectrochemical platform based on cyclometalated iridium (III) complex for bioanalysis. Anal Chem 89:11098–11106

    Article  CAS  Google Scholar 

  • Li Y, Chen FT, Luan ZZ et al (2018a) A versatile cathodic “signal-on” photoelectrochemical platform based on a dual-signal amplification strategy. Biosens Bioelectron 119:63–69

    Article  CAS  Google Scholar 

  • Li C, Hu XL, Lu JY et al (2018b) Design of DNA nanostructure-based interfacial probes for the electrochemical detection of nucleic acids directly in whole blood. Chem Sci 9:979–984

    Article  CAS  Google Scholar 

  • Li MJ, Xiong C, Zheng YN et al (2018c) Ultrasensitive photoelectrochemical biosensor based on DNA tetrahedron as nanocarrier for efficient immobilization of CdTe QDs-methylene blue as signal probe with near-zero background noise. Anal Chem 90:8211–8216

    Article  CAS  Google Scholar 

  • Lv SZ, Zhang KY, Zeng YY et al (2018) Double photosystems-based ‘Z-scheme’ photoelectrochemical sensing mode for ultrasensitive detection of disease biomarker accompanying three-dimensional DNA walker. Anal Chem 90:7086–7093

    Article  CAS  Google Scholar 

  • Meng HM, Liu H, Kuai HL et al (2016) Aptamer-integrated DNA nanostructures for biosensing, bioimaging and cancer therapy. Chem Soc Rev 45:2583–2602

    Article  CAS  Google Scholar 

  • Qiu Z, Shu J, Tang D (2018) Near-infrared-to-ultraviolet light-mediated photoelectrochemical aptasensing platform for cancer biomarker based on core-shell NaYF4:Yb, Tm@TiO2 upconversion microrods. Anal Chem 90:1021–1028

    Article  CAS  Google Scholar 

  • Qu YQ, Duan XF (2013) Progress, challenge and perspective of heterogeneous photocatalysts. Chem Soc Rev 42:2568–2580

    Article  CAS  Google Scholar 

  • Shen QM, Han L, Fan GH et al (2015) “Signal-on” photoelectrochemical biosensor for sensitive detection of human T-Cell lymphotropic virus type II DNA: dual signal amplification strategy integrating enzymatic amplification with terminal deoxynucleotidyl transferase-mediated extension. Anal Chem 87:4949–4956

    Article  CAS  Google Scholar 

  • Shen HJ, Wang YQ, Wang J et al (2018) Emerging biomimetic applications of DNA nanotechnology. ACS Appl Mater Interface. https://doi.org/10.1021/acsami.8b06175

    Article  Google Scholar 

  • Shi XM, Fan GC, Shen QM et al (2016) Photoelectrochemical DNA biosensor based on dual-signal amplification strategy integrating inorganic-organic nanocomposites sensitization with λ-exonuclease-assisted target recycling. ACS Appl Mater Interfaces 8:35091–35098

    Article  CAS  Google Scholar 

  • Shi XM, Fan GC, Tang X et al (2018) Ultrasensitive photoelectrochemical biosensor for the detection of HTLV-I DNA: a cascade signal amplification strategy integrating λ-exonuclease aided target recycling with hybridization chain reaction and enzyme catalysis. Biosens Bioelectron 109:190–196

    Article  CAS  Google Scholar 

  • Wang HH, Li MJ, Zheng YN et al (2018) An ultrasensitive photoelectrochemical biosensor based on [Ru(dcbpy)2dppz]2+/Rose Bengal dyes co-sensitized fullerene for DNA detection. Biosens Bioelectron 120:71–76

    Article  CAS  Google Scholar 

  • Willner I, Patolsky F, Wasserman J et al (2001) Photoelectrochemistry with controlled DNA-cross-linked CdS nanoparticle Arrays. Angew Chem Int Ed 40:1913–1916

    Article  Google Scholar 

  • Xiong EH, Yan XX, Zhang XH et al (2018) A new photoelectrochemical biosensor for ultrasensitive determination of nucleic acids based on a three-stage cascade signal amplification strategy. Analyst 143:2799–2806

    Article  CAS  Google Scholar 

  • Yan K, Wang R, Zhang JD et al (2014) A photoelectrochemical biosensor for o-aminophenol based on assembling of CdSe and DNA on TiO2 film electrode. Biosens Bioelectron 53:301–304

    Article  CAS  Google Scholar 

  • Ye C, Wang MQ, Gao ZF et al (2016) Ligating dopamine as signal trigger onto the substrate via metal-catalyst-free click chemistry for “signal-on” photoelectrochemical sensing of ultralow MicroRNA levels. Anal Chem 88:11444–11449

    Article  CAS  Google Scholar 

  • Ye C, Wang MQ, Luo HQ et al (2017) Label-free photoelectrochemical “Off-On” platform coupled with G-wire-enhanced strategy for highly sensitive microRNA sensing in cancer cells. Anal Chem 89:11697–11702

    Article  CAS  Google Scholar 

  • Youngblood WJ, Lee SHA, Kobayashi Y et al (2009) Photoassisted overall water splitting in a visible light-absorbing dye-sensitized photoelectrochemical cell. J Am Chem Soc 131:926–927

    Article  CAS  Google Scholar 

  • Yu X, Wang Y, Chen X et al (2015) White-light-exciting, layer-by-layer-assembled ZnCdHgSe quantum dots/polymerized ionic liquid hybrid film for highly sensitive photoelectrochemical immunosensing of neuron specific enolase. Anal Chem 87:4237–4244

    Article  CAS  Google Scholar 

  • Zhang XR, Li SG, Jin X et al (2011) A new photoelectrochemical aptasensor for the detection of thrombin based on functionalized graphene and CdSe nanoparticles multilayers. Chem Commun 47(17):4929–4931

    Article  CAS  Google Scholar 

  • Zhang XR, Xu YP, Yang YQ et al (2012) A new signal-on photoelectrochemical biosensor based on a graphene/quantum-dot nanocomposite amplified by the dual-quenched effect of bipyridinium relay and AuNPs. Chem Eur J 18:16411–16418

    Article  CAS  Google Scholar 

  • Zhang XR, Guo YS, Liu MS et al (2013a) Photoelectrochemically active species and photoelectrochemical biosensors. Rsc Adv 3:2846–2857

    Article  CAS  Google Scholar 

  • Zhang XR, Xu YP, Zhao YQ et al (2013b) A new photoelectrochemical biosensors based on DNA conformational changes and isothermal circular strand-displacement polymerization reaction. Biosens Bioelectron 39:338–341

    Article  CAS  Google Scholar 

  • Zhang XR, Chen J, Liu HX et al (2015) Quartz crystal microbalance detection of protein amplified by nicked circling, rolling circle amplification and biocatalytic precipitation. Biosens Bioelectron 65:341–345

    Article  Google Scholar 

  • Zhang N, Zhang L, Ruan YF et al (2017) Quantum-dots-based photoelectrochemical bioanalysis highlighted with recent examples. Biosens Bioelectron 94:207–218

    Article  CAS  Google Scholar 

  • Zhang K, Lv S, Lu M et al (2018) Photoelectrochemical biosensing of disease marker on p-type Cu-doped Zn0.3Cd0.7S based on RCA and exonuclease III amplification. Biosens Bioelectron 117:590–596

    Article  CAS  Google Scholar 

  • Zhao WW, Dong XY, Wang J et al (2012a) Immunogold labeling-induced synergy effect for amplified photoelectrochemical immunoassay of prostate-specific antigen. Chem Commun 48:5253–5255

    Article  CAS  Google Scholar 

  • Zhao WW, Ma ZY, Yu PP et al (2012b) Highly sensitive photoelectrochemical immunoassay with enhanced amplification using horseradish peroxidase induced biocatalytic precipitation on a CdS quantum dots multilayer electrode. Anal Chem 84:917–923

    Article  Google Scholar 

  • Zhao WW, Shan S, Ma ZY et al (2013) Acetylcholine esterase antibodies on BiOI nanoflakes/TiO2 nanoparticles electrode: a case of application for general photoelectrochemical enzymatic analysis. Anal Chem 85:11686–11690

    Article  CAS  Google Scholar 

  • Zhao WW, Xu JJ, Chen HY (2015a) Photoelectrochemical bioanalysis: the state of the art. Chem Soc Rev 46:729–741

    Article  CAS  Google Scholar 

  • Zhao YY, Chen F, Li Q et al (2015b) Isothermal amplification of nucleic acids. Chem Rev 115:12491–12545

    Article  CAS  Google Scholar 

  • Zhao Y, Tan L, Gao XS et al (2018) Silver nanoclusters-assisted ion-exchange reaction with CdTe quantum dots for photoelectrochemical detection of adenosine by target-triggering multiple-cycle amplification strategy. Biosens Bioelectron 110:239–245

    Article  CAS  Google Scholar 

  • Zheng YN, Liang WB, Xiong CY et al (2016) Self-enhanced ultrasensitive photoelectrochemical biosensor based on nanocapsule packaging both donor-acceptor-type photoactive material and its sensitizer. Anal Chem 88:8698–8705

    Article  CAS  Google Scholar 

  • Zheng YN, Liang WB, Xiong CY et al (2017) Universal ratiometric photoelectrochemical bioassay with target nucleotide transduction amplification and electron-transfer tunneling distance regulation strategies for ultrasensitive determination of microRNA in cells. Anal Chem 89:9445–9451

    Article  CAS  Google Scholar 

  • Zhuang JY, Lai WQ, Xu MD et al (2015) Plasmonic AuNP/gC3N4 nanohybrid-based photoelectrochemical sensing platform for ultrasensitive monitoring of polynucleotide kinase activity accompanying DNAzyme-catalyzed precipitation amplification. ACS Appl Mater Interfaces 7:8330–8338

    Article  CAS  Google Scholar 

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Correspondence to Xiaoru Zhang .

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Zhang, X. (2019). The Application of DNA Amplification Strategies in the Field of Photoelectrochemical Biosensor. In: Zhang, S., Bi, S., Song, X. (eds) Nucleic Acid Amplification Strategies for Biosensing, Bioimaging and Biomedicine. Springer, Singapore. https://doi.org/10.1007/978-981-13-7044-1_8

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