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Nanobiodevices for Cancer Diagnostics and Stem Cell Therapeutics

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Applications of Microfluidic Systems in Biology and Medicine

Part of the book series: Bioanalysis ((BIOANALYSIS,volume 7))

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Abstract

This chapter describes the potential of multifunctional nanobiodevices in combination with quantum dots (QDs) to meet the requirements of diagnostic and theranostic systems. Nanobiodevices are primed to be powerful tools to provide the basis for the detection of small amounts of samples and simple operation. QDs can be utilized in these devices as bio-probes or labels for biological imaging of single molecules and cells. They have developed into new formats of biosensing to push the limits of detection. QDs has been also demonstrated to construct a multifunctional nanoplatform for stem cell transplantation and labeling with diagnostic and therapeutic modalities. The potential clinical applications of QDs have been expanded by the development of considerably low cytotoxicity QDs that do not include cadmium or selenium, as well as the development of longwave fluorescence QDs with strong permeability into the body. It provides the promising applications and further perspectives on future regenerative medicine.

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Authors and Affiliations

  1. Institute of Innovation for Future Society, Nagoya University, Nagoya, Japan

    Daisuke Onoshima, Hiroshi Yukawa & Yoshinobu Baba

  2. ImPACT Research Center for Advanced Nanobiodevices, Nagoya University, Nagoya, Japan

    Daisuke Onoshima, Hiroshi Yukawa & Yoshinobu Baba

  3. Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya, Japan

    Hiroshi Yukawa & Yoshinobu Baba

  4. Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Takamatsu, Japan

    Yoshinobu Baba

  5. School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China

    Yoshinobu Baba

Authors
  1. Daisuke Onoshima
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  2. Hiroshi Yukawa
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  3. Yoshinobu Baba
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Corresponding authors

Correspondence to Daisuke Onoshima or Hiroshi Yukawa .

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Editors and Affiliations

  1. Division of Applied Chemistry, Faculty of Engineering, Hokkaido University, Sapporo, Japan

    Manabu Tokeshi

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Onoshima, D., Yukawa, H., Baba, Y. (2019). Nanobiodevices for Cancer Diagnostics and Stem Cell Therapeutics. In: Tokeshi, M. (eds) Applications of Microfluidic Systems in Biology and Medicine . Bioanalysis, vol 7. Springer, Singapore. https://doi.org/10.1007/978-981-13-6229-3_10

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