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Coloboma of the Choroid

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Surgical Retina

Part of the book series: Retina Atlas ((RA))

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Abstract

Colobomas of the choroid are a subset of uveal colobomas which result from disruption of the normal process of ocular development during organogenesis. This disruption causes a thinning or absence of a portion of the choroid. Choroidal colobomas may be isolated, associated with other ocular features such as microphthalmos, or associated with systemic features such as papillorenal syndrome and CHARGE syndrome.

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References

  1. Chang L, Blain D, Bertuzzi S, Brooks BP. Uveal coloboma: clinical and basic science update. Curr Opin Ophthalmol. 2006;17(5):447–70.

    Article  Google Scholar 

  2. Merlob P, Stahl B, Klinger G. Tetrada of the possible mycophenolate mofetil embryopathy: a review. Reprod Toxicol. 2009;28(1):105–8. https://doi.org/10.1016/j.reprotox.2009.02.007. Epub 2009 Feb 25.

    Article  CAS  PubMed  Google Scholar 

  3. The Online Mendelian Inheritance in Man Database. Omim.org. Accessed May 2017.

  4. Schubert HD. Structural organization of choroidal colobomas of young and adult patients and mechanism of retinal detachment. Trans Am Ophthalmol Soc. 2005;103:457–72.

    PubMed  PubMed Central  Google Scholar 

  5. Font RL, Zimmerman LE. Intrascleral smooth muscle in coloboma of the optic disk. Electron microscopic verification. Am J Ophthalmol. 1971;72(2):452–7.

    Article  CAS  Google Scholar 

  6. Gopal L, Khan B, Jain S, Prakash VS. A clinical and optical coherence tomography study of the margins of choroidal colobomas. Ophthalmology. 2007;114(3):571–80.

    Article  Google Scholar 

  7. Shah SP, Taylor AE, Sowden JC, et al. Anophthalmos, microphthalmos, and coloboma in the United kingdom: clinical features, results of investigations, and early management. Ophthalmology. 2012;119(2):362–8. https://doi.org/10.1016/j.ophtha.2011.07.039. Epub 2011 Nov 4.

    Article  PubMed  Google Scholar 

  8. Varghese M, Kavalakatt JA, Pandey S, Kolath JJ. Macular coloboma. Oman J Ophthalmol. 2016;9(1):67–8. https://doi.org/10.4103/0974-620X.176126.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Tripathy K, Chawla R, Sharma YR, et al. Prophylactic laser photocoagulation of fundal coloboma: does it really help? Acta Ophthalmol. 2016;94(8):e809–10. https://doi.org/10.1111/aos.12975. Epub 2016 Jan 29.

    Article  PubMed  Google Scholar 

  10. Uhumwangho OM, Jalali S. Chorioretinal coloboma in a paediatric population. Eye (Lond). 2014;28(6):728–33. https://doi.org/10.1038/eye.2014.61. Epub 2014 Mar 28.

    Article  CAS  Google Scholar 

  11. Fu SJ, Weng NQ. Retinal detachment associated with coloboma of choroid. Zhonghua Yan Ke Za Zhi. 1989;25(1):15–7.

    CAS  PubMed  Google Scholar 

  12. Abouammoh MA, Alsulaiman SM, Gupta VS, Younis A, Chhablani J, Hussein A, Casella AM, Banker AS, Arevalo JF; King Khaled Eye Specialist Hospital (KKESH) International Collaborative Retina Study Group. Surgical outcomes and complications of rhegmatogenous retinal detachment in eyes with chorioretinal coloboma: the results of the KKESH International Collaborative Retina Study Group. Retina. 2017. doi: https://doi.org/10.1097/IAE.0000000000001444. [Epub ahead of print].

    Article  Google Scholar 

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Correspondence to J. Fernando Arevalo .

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Carey, A., Arevalo, J.F. (2019). Coloboma of the Choroid. In: Ohji, M. (eds) Surgical Retina. Retina Atlas. Springer, Singapore. https://doi.org/10.1007/978-981-13-6214-9_8

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  • DOI: https://doi.org/10.1007/978-981-13-6214-9_8

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-13-6213-2

  • Online ISBN: 978-981-13-6214-9

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