Abstract
In recent years, there has been a wide range of studies about demonstration of micro-plasma safety on cells. This study emphasizes micro-plasma effects on cells, especially proliferation and migration, by using Western Blot technique and Image J analysis software determines the relative density of protein γ-H2AX (the protein marks a deoxyribonucleic acid—DNA breaks) in groups of muscle cell of mice (L929) treated by N2/Ar micro-plasma in different exposure time (0, 5, 10 and 15 s) with capacity 17 W. Analysis of results aims to evaluate and compare micro-plasma safety in various exposure time. In conclusion, by those results lead to confirm the safety of micro-plasma at the molecular level in terms of cell viability, proliferation and migration. Thanks to micro-plasma effects on cell, micro-plasma is used in wound healing, sterilization, and can even be used to kill cancer cells.
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Acknowledgements
This result is funded by Ho Chi Minh City University of Technology-VNU-HCM under grant number SVCQ-2017-KHUD-98.
Conflict of Interest Statement The authors declare that they have no conflict of interest.
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Hien, N.T.M. et al. (2020). Bio-safety and Bio-efficiency of Micro-plasma Exposure to Fibroblast Cells L929. In: Van Toi , V., Le, T., Ngo, H., Nguyen, TH. (eds) 7th International Conference on the Development of Biomedical Engineering in Vietnam (BME7). BME 2018. IFMBE Proceedings, vol 69. Springer, Singapore. https://doi.org/10.1007/978-981-13-5859-3_39
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DOI: https://doi.org/10.1007/978-981-13-5859-3_39
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