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Functions of Cell Death and DNA Damage-Related Signaling Pathways in the Regulation of Toxicity of Environmental Toxicants or Stresses

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Molecular Toxicology in Caenorhabditis elegans

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Abstract

Cell death and DNA damage are central biological events in organisms. Meanwhile, they also have another important role in regulating the toxicity formation in nematodes exposed to various toxicants or stresses. We here introduced and discussed the role of cell death and DNA damage-related signaling pathway in the regulation of toxicity of environmental toxicants or stresses and the underlying mechanisms. The involvement of DNA replication stress-related signal and telomere-related signal in regulating toxicity of environmental toxicants or stresses was also introduced and discussed.

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Authors and Affiliations

  1. School of Medicine, Southeast University, Nanjing, China

    Dayong Wang

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  1. Dayong Wang
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Wang, D. (2019). Functions of Cell Death and DNA Damage-Related Signaling Pathways in the Regulation of Toxicity of Environmental Toxicants or Stresses. In: Molecular Toxicology in Caenorhabditis elegans. Springer, Singapore. https://doi.org/10.1007/978-981-13-3633-1_7

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