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Functions of Development-Related Signaling Pathways in the Regulation of Toxicity of Environmental Toxicants or Stresses

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Molecular Toxicology in Caenorhabditis elegans

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Abstract

Although the development-related signaling pathways are normally considered to be required for certain aspects of development, some development-related signaling pathways may participate in regulating the toxicity of environmental toxicants or stresses under certain conditions. In this chapter, we introduced and discussed the involvement of Wnt, TGF-β, Notch, and developmental timing control-related signaling pathways in the regulation of toxicity of environmental toxicants or stresses and the underlying mechanisms in nematodes. The information introduced here further confirms the potential dual roles of some developmental related signals in the toxicity induction of environmental toxicants or stresses.

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Authors and Affiliations

  1. School of Medicine, Southeast University, Nanjing, China

    Dayong Wang

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  1. Dayong Wang
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Wang, D. (2019). Functions of Development-Related Signaling Pathways in the Regulation of Toxicity of Environmental Toxicants or Stresses. In: Molecular Toxicology in Caenorhabditis elegans. Springer, Singapore. https://doi.org/10.1007/978-981-13-3633-1_6

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