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Genetics, Ageing and Human Health

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Models, Molecules and Mechanisms in Biogerontology

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Abstract

Ageing is a gradual impairment of physiological processes, leading to compromised cellular functions enhancing susceptibility to death. Ageing also becomes the primary cause of major human pathological disorders, comprising neurodegenerative diseases, cardiovascular disorders, cancer, and many more. In the developed as well as the developing world, ageing represents the biggest cause of illness and mortality. Ageing can be controlled to some extent by targeting genetic corridors and biochemical pathways implicated with human health. The idea of targeting ageing by reversing the pathogenesis of diseases seems to be promising but poses its own challenges. This chapter elucidates the genetic disorders affecting the aged people highlighting the challenges related to their healthcare system.

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Author information

Authors and Affiliations

  1. Centre for Interdisciplinary Research in Basic Sciences, New Delhi, India

    Parvez Khan, Aarfa Queen, Md. Imtaiyaz Hassan & Sher Ali

  2. Department of Chemistry, Jamia Millia Islamia, New Delhi, India

    Aarfa Queen

Authors
  1. Parvez Khan
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  2. Aarfa Queen
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  3. Md. Imtaiyaz Hassan
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  4. Sher Ali
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Corresponding author

Correspondence to Sher Ali .

Editor information

Editors and Affiliations

  1. School of Life Sciences, Jawaharlal Nehru University, New Delhi, India

    Pramod C. Rath

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Khan, P., Queen, A., Hassan, M.I., Ali, S. (2019). Genetics, Ageing and Human Health. In: Rath, P. (eds) Models, Molecules and Mechanisms in Biogerontology. Springer, Singapore. https://doi.org/10.1007/978-981-13-3585-3_10

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