Cervical Squamous Intraepithelial Lesions: A Pathologist’s Perspective

  • Charanjeet Singh
  • Grace N. KimEmail author


Human papillomavirus (HPV) infection is associated with cervical squamous carcinoma and adenocarcinoma and their precursors. This chapter underscores the role of pathologists in morphologic evaluation and ancillary testing of cervical tissue, which is paramount toward successful implementation of cervical cancer screening protocols. Cytohistologic criteria for the precursor lesions (low-grade squamous intraepithelial lesion, high-grade squamous intraepithelial lesion, and SMILE), along with various methods for HPV testing, are herein discussed.




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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  1. 1.Department of PathologyFlorida HospitalOrlandoUSA
  2. 2.Department of PathologyUniversity of Central FloridaOrlandoUSA
  3. 3.Department of PathologyLAC+USC Medical CenterLos AngelesUSA
  4. 4.Department of PathologyKeck Hospital of USCLos AngelesUSA

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