Abstract
Epithelial carcinomas constitute the majority of all cases of esophageal cancer. While squamous cell carcinoma (SCC) typically occurs throughout the esophagus (commonest middle third), adenocarcinomas mostly occur in the distal one-third and the esophagogastric junction (EGJ). All adenocarcinomas involving the EGJ are included under the group of EGJ carcinomas; these include esophageal carcinomas, gastric carcinomas and true carcinomas of the cardia. It is rare for lower esophageal SCCs to involve the EGJ; hence all discussion of EGJ carcinomas refers to adenocarcinoma. The incidence of adenocarcinoma has increased, while that of SCC has declined steadily in the Western population, in the last few decades [1, 2]. Hence EGJ carcinoma has become a tumour of increasing importance over the last few decades. The reasons for the increasing focus on these tumours include the rising incidence in the Western world, the controversies in classifications, the generally poor prognosis and major differences in the treatment and outcomes as compared to squamous cell carcinoma of the esophagus.
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Singh, R.K. (2019). Esophagogastric Junction (EGJ) Carcinoma: An Updated Review. In: Sahni, P., Pal, S. (eds) GI Surgery Annual. GI Surgery Annual, vol 25. Springer, Singapore. https://doi.org/10.1007/978-981-13-3227-2_1
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