Abstract
Quality of life (QoL) assessment of cancer patients gives a direct and subjective experience of his/her health status. Head and neck cancer patients, more specifically those with laryngeal and hypopharyngeal cancers, can face several issues which impact their physical, social and psychological aspects of daily living. The disease and its treatments can profoundly affect the speech and swallowing functions.
As a patient-reported outcome, QoL is devoid of any physician bias and has the potential benefits to assess the functional aspects of daily living. It is observed in clinical trials that patients who show better scores on QoL assessments can gain with improved survival. Head and neck oncologists should utilise the QoL instruments in conjunction with survival and morbidity assessments in the clinical practice.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Study protocol for the World Health Organization project to develop a Quality of Life assessment instrument (WHOQOL). Qual Life Res. 1993;2:153–9.
Singer S, Langedijk J, Yarom N. Assessing and improving quality of life in patients with head and neck cancer. ASCO Educ Book. 2013:e2301–e235. https://doi.org/10.1200/EdBook_AM.2013.33.e230.
Ojo B, Genden EM, Teng MS, Milbury K, Misiukiewicz KJ, Badr H. A systematic review of head and neck cancer quality of life assessment instruments. Oral Oncol. 2012;48:923–37.
Bjordal K, Bottomley A. Making advances in quality of life studies in head and neck cancer. Int J Radiat Oncol Biol Phys. 2017;97:659–61.
RamÃrez MJ, Ferriol EE, Doménech FG, et al. Psychosocial adjustment in patient surgically treated for laryngeal cancer. Otolaryngol Head Neck Surg. 2003;129:92–7.
Aaronson NK, Ahmedzai S, Bergman B, et al. The European Organization for research and treatment of cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst. 1993;85:365–76.
Cella DF, Tulsky DS, Gray G, et al. The functional assessment of cancer therapy scale: development and validation of the general measure. J Clin Oncol. 1993;11:570–9.
Luckett T, King MT, Butow PN, Oguchi M, Rankin N, Price MA, Hackl NA, Heading G. Choosing between the EORTC QLQ-C30 and FACT-G for measuring health-related quality of life in cancer clinical research: issues, evidence and recommendations. Ann Oncol. 2011;22:2179–90.
Bansal M, Mohanti BK, Shah N, Chaudhry R, Bahadur S, Shukla NK. Radiation related morbidities and their impact on quality of life in head and neck cancer patients receiving radical radiotherapy. Qual Life Res. 2004;13:481–8.
Chawla S, Mohanti BK, Rakshak M, Saxena S, Rath GK, Bahadur S. Temporal assessment of quality of life of head and neck cancer patients receiving radical radiotherapy. Qual Life Res. 1999;8:73–8.
Guibert M, Lepage B, Woisard V, Rives M, Serrano E, Vergez S. Quality of life in patients treated for advanced hypopharyngeal or laryngeal cancer. Eur Ann Otolaryngol Head Neck Dis. 2011;128:218–23.
The Department of Veterans Affairs Laryngeal Cancer Study Group. Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer. N Engl J Med. 1991;324:1685–90.
Lefebvre JL, Chevalier D, Luboinski B, Kirkpatrick A, Collette L, Sahmoud T. Larynx preservation in pyriform sinus cancer: preliminary results of a European Organization for Research and Treatment of Cancer phase III trial. EORTC Head and Neck Cancer Cooperative Group. J Natl Cancer Inst. 1996;88(13):890–9.
Lefebvre JL, Ang KK, Larynx Preservation Consensus Panel. Larynx preservation clinical trial design: key issues and recommendations—a consensus panel summary. Head Neck. 2009;31:429–41.
Rosenthal DI, Mohamed AS, Weber RS, Garden AS, Sevak PR, Kies MS, Morrison WH, Lewin JS, El-Naggar AK, Ginsberg LE, Kocak-Uzel E, Ang KK, Fuller CD. Long-term outcomes after surgical or nonsurgical initial therapy for patients with T4 squamous cell carcinoma of the larynx: a 3-decade survey. Cancer. 2015;121:1608–19.
Takes RP, Strojan P, Silver CE, Bradley PJ, Haigentz M Jr, Wolf GT, Shaha AR, Hartl DM, Olofsson J, Langendijk JA, Rinaldo A, Ferlito A, International Head and Neck Scientific Group. Current trends in initial management of hypopharyngeal cancer: the declining use of open surgery. Head Neck. 2012;34:270–81.
Guibert M, Lepage B, Woisard V, Rives M, Serrano E, Vergez S. Quality of life in patients treated for advanced hypopharyngeal or laryngeal cancer. Eur Ann Otorhinolaryngol Head Neck Dis. 2011;128:218–23.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 The Author(s)
About this chapter
Cite this chapter
Mohanti, B.K. (2019). Quality of Life. In: Bahadur, S., Thakar, A., Mohanti, B. (eds) Carcinoma of the Larynx and Hypopharynx . Springer, Singapore. https://doi.org/10.1007/978-981-13-3110-7_17
Download citation
DOI: https://doi.org/10.1007/978-981-13-3110-7_17
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-13-3109-1
Online ISBN: 978-981-13-3110-7
eBook Packages: MedicineMedicine (R0)