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Complications of Early Pregnancy and Gestational Trophoblastic Diseases

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Gynecologic and Obstetric Pathology, Volume 2

Abstract

Placenta plays a crucial role in the development of the fetus. By connecting the fetus to the maternal circulation, it allows provision of oxygen and nutrients to the fetus while removing carbon dioxide and metabolic wastes. The placenta also provides essential hormones for the pregnancy and enables immunological protection for the fetus against infection and rejection by the maternal immune system. In this chapter, pathology of abortions as well as gestational trophoblastic diseases is discussed. Gestational trophoblastic diseases encompass a family of aggressive neoplasms, nonneoplastic lesions, and lesions with malignant potential that arise from various types of placental trophoblasts and may pose challenging problems in differential diagnoses in daily pathology practice.

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Authors and Affiliations

  1. Department of Pathology, The University of Hong Kong, Queen Mary Hospital, Hong Kong, SAR, China

    Philip P. C. Ip & Annie N. Y. Cheung

  2. Department of Pathology, HKU-Shenzhen Hospital, Shenzhen, China

    Yan Wang & Annie N. Y. Cheung

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  1. Philip P. C. Ip
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  2. Yan Wang
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Correspondence to Annie N. Y. Cheung .

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Editors and Affiliations

  1. Department of Pathology, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX, USA

    Wenxin Zheng

  2. Department of Pathology, University of California San Diego, San Diego, CA, USA

    Oluwole Fadare

  3. Department of Pathology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA

    Charles Matthew Quick

  4. Department of Pathology, Peking University People’s Hospital, Beijing, China

    Danhua Shen

  5. Department of Obstetrics and Gynecology, Tianjin Gynecologic and Obstetrics Central Hospital, Tianjin, China

    Donghui Guo

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Ip, P.P.C., Wang, Y., Cheung, A.N.Y. (2019). Complications of Early Pregnancy and Gestational Trophoblastic Diseases. In: Zheng, W., Fadare, O., Quick, C., Shen, D., Guo, D. (eds) Gynecologic and Obstetric Pathology, Volume 2. Springer, Singapore. https://doi.org/10.1007/978-981-13-3019-3_13

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