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Biochemistry and Cell Biology of Ageing: Part I Biomedical Science pp 323–350Cite as

Signal Transduction Pathways in Ageing

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Part of the book series: Subcellular Biochemistry ((SCBI,volume 90))

Abstract

It is now widely recognised that ageing and its associated functional decline are regulated by a wide range of molecules that fit into specific cellular pathways. Here, we describe several of the evolutionary conserved cellular signalling pathways that govern organismal ageing and discuss how their identification, and work on the individual molecules that contribute to them, has aided in the design of therapeutic strategies to alleviate the adverse effects of ageing and age-related disease.

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Authors and Affiliations

  1. School of Life and Health Sciences, Aston University, Birmingham, UK

    Cathy Slack

  2. School of Biosciences, University of Kent, Canterbury, Kent, UK

    Jennifer Tullet

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  1. Cathy Slack
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  2. Jennifer Tullet
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Correspondence to Cathy Slack .

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  1. Institute of Molecular Physiology, Johannes Gutenberg University, Mainz, Germany

    J. Robin Harris

  2. Newcastle University, Newcastle upon Tyne, UK

    Viktor I. Korolchuk

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Slack, C., Tullet, J. (2018). Signal Transduction Pathways in Ageing. In: Harris, J., Korolchuk, V. (eds) Biochemistry and Cell Biology of Ageing: Part I Biomedical Science. Subcellular Biochemistry, vol 90. Springer, Singapore. https://doi.org/10.1007/978-981-13-2835-0_11

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