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Quorum Sensing and Biofilm Disassembly Process in Pseudomonas aeruginosa, Staphylococcus aureus and Xanthomonas campestris

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Implication of Quorum Sensing System in Biofilm Formation and Virulence

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Abstract

Quorum sensing (QS) is a cooperative activity among bacterial cells that is mediated by extracellular cell signaling biomolecules and regulates multiple social traits like biofilm. Similar to QS, biofilm formation is also a cooperative activity among bacterial cell population that leads to formation of extracellular matrix in which bacterial cells are living embedded. Multiple findings intuitively indicate that QS may regulate biofilm formation when cell density of bacterial populations reaches at threshold levels.

However, a group of studies provide convincing evidences that QS initiates in established biofilm and leads to maturation and dispersion of biofilm. This chapter will explain the emerging concepts that QS regulates biofilm disassembly process using three pathogenic bacteria (Pseudomonas aeruginosa, Staphylococcus aureus and Xanthomonas campestris) as example.

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Author information

Authors and Affiliations

  1. Molecular Biology Unit, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India

    Santosh Kumar Singh

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  1. Santosh Kumar Singh
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Editors and Affiliations

  1. Department of Biotechnology, Krishna University, Machilipatnam, Andhra Pradesh, India

    Pallaval Veera Bramhachari

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Singh, S.K. (2018). Quorum Sensing and Biofilm Disassembly Process in Pseudomonas aeruginosa, Staphylococcus aureus and Xanthomonas campestris . In: Pallaval Veera Bramhachari (eds) Implication of Quorum Sensing System in Biofilm Formation and Virulence. Springer, Singapore. https://doi.org/10.1007/978-981-13-2429-1_19

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