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Biomarkers for “Cause of Death”

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Forensic Medicine and Human Cell Research

Part of the book series: Current Human Cell Research and Applications ((CHCRA))

Abstract

For forensic pathologists, the most important practice is clarifying the “cause of death” of victims at autopsy. But it is sometimes difficult to determine the cause of death or forensic important matters (e.g., postmortem interval (PMI)) by only gross dissection and microscopic examinations.

Biomarkers are considered to be useful to achieve the purpose.

In this chapter, we introduce our part of works about trying to discover biomarkers for some causes of death (sudden cardiac death, heatstroke (HS), and polypharmacy) and PMI by using DNA analysis method or metabolomics analysis method using gas chromatography-tandem mass spectrometry (GC-MS/MS). In addition, we introduce hair imaging analysis for substance abuse by matrix-assisted laser desorption/ionization imaging MS.

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Authors and Affiliations

  1. Department of Legal Medicine, Osaka Medical College, Takatsuki, Osaka, Japan

    Takako Sato & Koichi Suzuki

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  1. Takako Sato
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Correspondence to Takako Sato .

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  1. Department of Legal Medicine, Osaka City University Medical School, Osaka, Japan

    Takaki Ishikawa

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Sato, T., Suzuki, K. (2019). Biomarkers for “Cause of Death”. In: Ishikawa, T. (eds) Forensic Medicine and Human Cell Research. Current Human Cell Research and Applications. Springer, Singapore. https://doi.org/10.1007/978-981-13-2297-6_1

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  • DOI: https://doi.org/10.1007/978-981-13-2297-6_1

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