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Acute Kidney Injury in Children Following Cardiopulmonary Bypass: A Call for Action

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Critical Care Pediatric Nephrology and Dialysis: A Practical Handbook

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Abstract

Acute kidney injury (AKI) occurs frequently in children undergoing surgery for complex congenital heart disease and is associated with poor outcomes. Unfortunately, despite several decades’ worth of data delineating a strong epidemiologic signal for both high incidence and association with outcomes such as prolonged mechanical ventilation, high infection rates, and increased rates of death, very little progress has been made in reducing the reach and sequelae of the disease. In this chapter, elements of pathophysiology and epidemiology will be integrated into the perspectives of past, present, and future patient care. Existing views of the etiology and management of AKI will be challenged—ultimately shifting the AKI paradigm toward highlighting avenues of research and patient management requiring broadscale, multidisciplinary study, investment, and progress.

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Author information

Authors and Affiliations

  1. Division of Critical Care Medicine, Children’s Healthcare of Atlanta, Atlanta, GA, USA

    Rajit K. Basu

  2. Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA

    Rajit K. Basu

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  1. Rajit K. Basu
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Correspondence to Rajit K. Basu .

Editor information

Editors and Affiliations

  1. Kidney & Urology Institute, Medanta, The Medicity Kidney & Urology Institute, Gurugram, Haryana, India

    Sidharth Kumar Sethi

  2. Department of Nephrology, Cleveland Clinic Akron General Medical center and Akron Children’s Hospital, Akron, OH, USA

    Rupesh Raina

  3. Red Cross War Memorial Children’s Hospital, University of Cape Town, Cape Town, South Africa

    Mignon McCulloch

  4. Pediatric Nephrology, Children’s Hospital of Richmond at the Virginia Commonwealth University, Richmond, VA, USA

    Timothy E. Bunchman

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Basu, R.K. (2019). Acute Kidney Injury in Children Following Cardiopulmonary Bypass: A Call for Action. In: Sethi, S., Raina, R., McCulloch, M., Bunchman, T. (eds) Critical Care Pediatric Nephrology and Dialysis: A Practical Handbook. Springer, Singapore. https://doi.org/10.1007/978-981-13-2276-1_19

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  • DOI: https://doi.org/10.1007/978-981-13-2276-1_19

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  • Publisher Name: Springer, Singapore

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  • Online ISBN: 978-981-13-2276-1

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