Abstract
Glaucoma is the leading cause of irreversible blindness [1], and it is a major public health issue. The pathological mechanism of glaucoma is not fully understood yet. In this chapter, we mainly focus on the glia cells which take part in the underlying mechanism of glaucoma.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Quigley HA, Broman AT. The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol. 2006;90:262–7.
Herculano-Houzel S. The glia/neuron ratio: how it varies uniformly across brain structures and species and what that means for brain physiology and evolution. Glia. 2014;62:1377–91.
Khakh BS, Sofroniew MV. Diversity of astrocyte functions and phenotypes in neural circuits. Nat Neurosci. 2015;18:942–52.
Davis CH, Kim KY, Bushong EA, et al. Transcellular degradation of axonal mitochondria. Proc Natl Acad Sci U S A. 2014;111:9633–8.
Davis CH, Marsh-Armstrong N. Discovery and implications of transcellular mitophagy. Autophagy. 2014;10:2383–4.
Hayakawa K, Esposito E, Wang X, et al. Transfer of mitochondria from astrocytes to neurons after stroke. Nature. 2016;535:551–5.
Nagelhus EA, Veruki ML, Torp R, et al. Aquaporin-4 water channel protein in the rat retina and optic nerve: polarized expression in Muller cells and fibrous astrocytes. J Neurosci. 1998;18:2506–19.
Li Y, Li D, Ying X, et al. An energy theory of glaucoma. Glia. 2015;63(9):1537–52.
Dai C, Khaw PT, Yin ZQ, Li D, Raisman G, Li Y. Olfactory ensheathing cells rescue optic nerve fibers in a rat glaucoma model. Transl Vis Sci Technol. 2012;1:3.
Islam MN, Das SR, Emin MT, et al. Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung injury. Nat Med. 2012;18:759–65.
Spees JL, Lee RH, Gregory CA. Mechanisms of mesenchymal stem/stromal cell function. Stem Cell Res Ther. 2016;7:125.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Singapore Pte Ltd.
About this chapter
Cite this chapter
Li, X., Wang, N. (2019). Energy Theory of Glaucoma. In: Wang, N. (eds) Intraocular and Intracranial Pressure Gradient in Glaucoma. Advances in Visual Science and Eye Diseases, vol 1. Springer, Singapore. https://doi.org/10.1007/978-981-13-2137-5_13
Download citation
DOI: https://doi.org/10.1007/978-981-13-2137-5_13
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-13-2136-8
Online ISBN: 978-981-13-2137-5
eBook Packages: MedicineMedicine (R0)