Abstract
The search for functional materials that repair and/or regenerate of biological tissues in a satisfactory manner has continually risen in the past few years. For such applications, composite materials are each time being better accepted, capable of merge properties from different materials. In this context, the purpose of this study is the development and mechanical characterization of bioactive composite films based on Poly(ε-caprolactone) and Biosilicate®, obtained from two different routes. Route 1 uses the solvent casting technique, and route 2 consists of phase precipitation followed by solvent casting. The mechanical tests show that route 1 presents samples more resistant than route 2, probably due to it high porosity levels. The addition of BS yielded an increase in Young’s modulus of around 46%, although the maximum stress and yield strength were reduced. Nevertheless, the mechanical properties of the developed materials are compatible with the biological tissues.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Gibson, R.F.: Principles of Composite Material Mechanics, 4 edn. CRC Press, Florida (2016)
Orefice, R.L., et al.: Biomateriais—fundamentos e aplicações, 1 edn. Guanabara Koogan, Belo Horizonte (2006)
Dash, T.K., Konkimalla, V.B.: Poly-є-caprolactone based formulations for drug delivery and tissue engineering: a review. J. Control. Release 158(1), 15–33 (2012)
Crovace, M.C., et al.: Biosilicate®—a multipurpose, highly bioactive glass ceramic. In vitro, in vivo and clinical trials. J. Non-Crystal. Solids 432(part A), 90–110 (2016)
Gabbai-Armelin, P.R., et al.: Injectable composites based on biosilicate® and alginate: handling and in vitro characterization. RSC Adv. 4(86), 45778–45785 (2014)
Kido, H.W., et al.: Porous poly (D, L-lactide-co-glycolide) acid/biosilicate® composite scaffolds for bone tissue engineering. J. Biomed. Mater. Res. B Appl. Biomater. 105(1), 63–71 (2015)
Santos, L.R., et al.: Preliminary in vitro biocompatibility study of chitosan/Biosilicate® composite membranes. In: Workshop de Biomateriais, Engenharia de Tecidos e Orgãos Artificiais 2015, OBI, vol. 1, p. 1. Campina Grande (2015)
Abedalwafa, M., et al.: Biodegradable poly-epsilon-caprolactone (PCL) for tissue engineering applications: a review. Rev. Adv. Mater. Sci. 34, 123–140 (2013)
Callister, W.D.: Materials Science and engineering: an introduction. 8 edn. Wiley Inc, Utah (2010)
Canevarolo, S.V.: Ciências dos Polímeros, 2nd edn. Artliber, Campinas (2007)
Chawla, Krishan Kumar: Composite Materials: Science and Engineering, 2nd edn. Springer, New York (1998)
Mohammadkhah, A., et al.: Fabrication and characterization of poly-(ε)-caprolactone and bioative glass composites for tissue engineering applications. Mater. Sci. Eng C 49, 632–639 (2015)
Poh, P.S.P., et al.: In vitro and in vivo bone formation potential of surface calcium phosphate-coated polycaprolactone/bioative glass composite scaffolds. Acta Biomater. 30, 319–333 (2016)
Leblon, C.E., et al.: In vitro comparative biodegradation analysis of salt-leached porous polymer scaffolds. J. Appl. Polym. Sci. 128(5), 2701–2712 (2013)
ASTM-D882-12. Standard test method for tensile properties of thin plastic sheeting. In: Book of Standards: ASTM International, vol. 8, no. 1 (2012)
Black, J., Hastings, G.: Handbook of Biomaterial Properties. Chapman & Hall, pp. 135–213. London (1998)
Ferreira, F.A, Simbara, M.M.O., Malmonge, S. M.: Estudo in vitro da degradação hidrolítica de polímeros utilizados em engenharia tecidual. In: 8o Congresso Latino Americano de Órgãos Artificiais, Biomateriais e Engenharia Tecidual, 2014, COLAOB. Rosário (2014)
Jo, J., et al.: In vitro/in vivo biocompatibility and mechanical properties of bioactive glass nanofiber and poly(ε-caprolactone) composite materials. J. Biomed. Mater. Res. Part B Appl. Biomater. 91, 231–220 (2009)
Liu, J., et al.: Microstructure and properties of polycaprolactone/calcium sulfate particle and whisker composites. Polym. Compos. 33(4), 501–508 (2012)
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Singapore Pte Ltd.
About this paper
Cite this paper
Weber, A.F., Monteiro, R.S., Malmonge, S.M., Souza, M.T., Petil, O., Daguano, J.K.M.B. (2019). Mechanical Evaluation of Poly-ε-Caprolactone and Biosilicate® Composites. In: Costa-Felix, R., Machado, J., Alvarenga, A. (eds) XXVI Brazilian Congress on Biomedical Engineering. IFMBE Proceedings, vol 70/1. Springer, Singapore. https://doi.org/10.1007/978-981-13-2119-1_14
Download citation
DOI: https://doi.org/10.1007/978-981-13-2119-1_14
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-13-2118-4
Online ISBN: 978-981-13-2119-1
eBook Packages: EngineeringEngineering (R0)