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The Potential Role of Stem Cell Reprogramming in Antiaging

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Molecular Basis and Emerging Strategies for Anti-aging Interventions

Abstract

Aging is a natural process defined as a progressive decline in physiological functions which lead to increased risk of diseases and death. Recent advances in antiaging intervention have focused on stem cell-based therapies and cell reprogramming. The development of stem cell reprogramming to fight the aging process has recently become important issue in antiaging strategies. Stem cell-based therapies and cell reprogramming have provided various strategies to alter somatic cell identity into induced-pluripotent stem cell. Stem cells are defined as pluripotent cells that possess both the abilities of self-renewal and differentiation toward numerous cell types. Cell reprogramming is simply composed of deleting cell memory and rewriting new identity of somatic cell. Stem cell reprogramming has provided enormous insight on regenerative medicine for antiaging. This chapter has focused on potential role of stem cell reprogramming to slow down aging process.

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Authors and Affiliations

  1. Faculty of Science, Department of Biology, Istanbul University, Istanbul, Turkey

    Banu Orta Yilmaz & Melike Erkan

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  1. Banu Orta Yilmaz
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  2. Melike Erkan
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Correspondence to Melike Erkan .

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Editors and Affiliations

  1. Department of Biochemistry, University of Allahabad, Allahabad, Uttar Pradesh, India

    Syed Ibrahim Rizvi

  2. Medical Biochemistry, Istanbul University, Cerrahpasa, Istanbul, Turkey

    Ufuk Çakatay

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Orta Yilmaz, B., Erkan, M. (2018). The Potential Role of Stem Cell Reprogramming in Antiaging. In: Rizvi, S., Çakatay, U. (eds) Molecular Basis and Emerging Strategies for Anti-aging Interventions. Springer, Singapore. https://doi.org/10.1007/978-981-13-1699-9_3

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