Role of Alcohol and Metabolic Diseases in Colorectal Carcinogenesis
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Alcohol consumption was significantly associated with a risk of colorectal cancer with a relative risk ranging from 1.10 to 1.44 depending on the amount of intake. However, light intake of alcohol was not associated with incidence of colorectal cancer. Metabolic syndrome was also significantly associated with a risk of colorectal cancer with a relative risk ranging from 1.25 to 1.41. Of the four components of metabolic syndrome, dysglycemia and obesity were particularly associated with colorectal cancer risk. High levels of serum triglyceride were associated with increased colorectal cancer risk. However, there was no apparent association between raised blood pressure and colorectal cancer risk.
KeywordsAlcohol Metabolic syndrome Colorectal cancer Relative risk Dysglycemia Obesity
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