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Progress of Genomics in Hypertension–Cardiac Hypertrophy

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Heart Genomics

Part of the book series: Translational Bioinformatics ((TRBIO,volume 16))

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Abstract

Hypertension is a common risk factor for cardiac hypertrophy, and the pathological process of hypertension to cardiac hypertrophy has been widely studied. Except for the classic proteins and its related signaling pathways involved in the process from hypertension to cardiac hypertrophy, the genetic basis and epigenetic mechanism have been hotpots in recent years. Herein, we provide a comprehensive overview of currently known genetic or epigenetic pathways involved in the progression from hypertension to cardiac hypertrophy.

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Acknowledgment

This chapter was modified from the paper published by our group in Non-coding RNA investigation (Xiaoyan Wang, Zhiwen Ding, Jian Wu, Shijun Wang, Yunzeng Zou), 13 September 2017; 1; 5). The related contents are reused with the permission.

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  1. Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biomedical Science, Fudan University, Shanghai, China

    Xiaoyan Wang & Yunzeng Zou

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  1. Xiaoyan Wang
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  2. Yunzeng Zou
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Correspondence to Yunzeng Zou .

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  1. Zhongshan Hospital, Fudan University, Shanghai, China

    Hong Jiang

  2. Zhongshan Hospital, Fudan University, Shanghai, China

    Ming Liu

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Wang, X., Zou, Y. (2018). Progress of Genomics in Hypertension–Cardiac Hypertrophy. In: Jiang, H., Liu, M. (eds) Heart Genomics. Translational Bioinformatics, vol 16. Springer, Singapore. https://doi.org/10.1007/978-981-13-1429-2_7

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