Circular RNAs pp 131-139 | Cite as

Circular RNA in Saliva

  • Farinaz Jafari Ghods
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1087)


Although the type and amount of salivary components are influenced by many factors, due to easy, quick, cheap, and noninvasive sampling method alongside with the existence of the vast majority of the substances found in peripheral blood and urine in it, in recent years saliva has been considered as an ideal biofluid for disease research. Salivary circular RNA (circRNA), as an endogenous RNA molecule with a great variety of regulatory potency, is becoming a novel focus for detecting wide range of local or systemic diseases. Expectantly, with characterization of many more circRNAs in saliva, their motifs, and target sites, they can be used routinely in personalized medicine.


Circular RNA Saliva Noninvasive sampling Biofluid 



The authors thank Prof. Dr. Ahad Jafari Ghods, MD., FACP, (Iran University of Medical Sciences) for critical reading and comments on the manuscript.

Competing Financial Interests

The author declares no competing financial interests.


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Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Farinaz Jafari Ghods
    • 1
  1. 1.Department of Molecular Biology and Genetics, Faculty of ScienceIstanbul UniversityIstanbulTurkey

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