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Biaryl Amino Acids and Their Surrogates: A Unique Class of Unnatural Amino Acid

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Designed Molecular Space in Material Science and Catalysis

Abstract

Unnatural amino acids have attracted extensive attention as potential building blocks for bioactive molecules, artificial peptides, and asymmetric catalysts in the context of fine organic synthesis. Biaryl amino acids, a unique class of unnatural amino acids possessing a biaryl moiety, permit the development of a variety of functional molecules by virtue of their structural features, including axial chirality. This chapter discusses typical examples of the synthesis and applications of biaryl amino acids as well as their surrogates, including the author’s approaches.

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Author information

Authors and Affiliations

  1. Department of Pharmaceutical Chemistry, Kyoto Pharmaceutical University, Kyoto, Japan

    Takumi Furuta

Authors
  1. Takumi Furuta
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Correspondence to Takumi Furuta .

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Editors and Affiliations

  1. Department of Environmental Science Graduate School of Fisheries and Environmental Sciences, Nagasaki University, Nagasaki, Japan

    Seiji Shirakawa

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Furuta, T. (2018). Biaryl Amino Acids and Their Surrogates: A Unique Class of Unnatural Amino Acid. In: Shirakawa, S. (eds) Designed Molecular Space in Material Science and Catalysis. Springer, Singapore. https://doi.org/10.1007/978-981-13-1256-4_6

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