Skip to main content

Sclerotherapy for Varicose Veins

  • Chapter
  • First Online:
Venous Disorders
  • 646 Accesses

Abstract

Sclerotherapy is the term used to describe the process of injecting sclerosant into varicose veins to cause obliteration of its endothelium, thus resulting in closure of veins. Sclerotherapy aims to achieve endoluminal damage and cause vein wall fibrosis [1–5].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 139.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. McPheeters HO. Treatment of varicose veins; a twenty-five year reflection. Minn Med. 1956;39:271–5.

    CAS  PubMed  Google Scholar 

  2. Sigg K, Zelikovski A. “Quick treatment”: a modified method of sclerotherapy of varicose veins. Vasa. 1975;4:73–8.

    CAS  PubMed  Google Scholar 

  3. Sigg K. Treatment of varicose veins and their complications. Dermatologica. 1950;100:315–20.

    Article  CAS  Google Scholar 

  4. Fegan WG, Fitzgerald DE, Beesley WH. A modern approach to the injection treatment of varicose veins and its applications in pregnant patients. Am Heart J. 1964;68:757–64.

    Article  CAS  Google Scholar 

  5. Fegan WG. Continuous compression technique of injecting varicose veins. Lancet. 1963;2:109–12.

    Article  CAS  Google Scholar 

  6. Tournay R. Indications for a single sclerosing therapy or diphasic combined surgery-sclerosing therapy in varicose veins. Zentralbl Phlebol. 1965;87:133–42.

    Google Scholar 

  7. Wallois P. Incidents and accidents in the sclerosing treatment of varicose veins and their prevention. Phlebologie. 1971;24:217.

    CAS  PubMed  Google Scholar 

  8. Cabrera Garido JR, Cabrera Garcia Olmedo JR, Olmedo DG. Nuevo metododel de esclerosis en las varices tronculares. Patol Vasculares. 1995;4:55–73.

    Google Scholar 

  9. Cabrera J, Redondo P, Becerra A, Garrido C, Cabrera J Jr, García-Olmedo MA, et al. Ultrasound-guided injection of polidocanol microfoam in the management of venous leg ulcers. Arch Dermatol. 2004;140:667–73.

    Article  Google Scholar 

  10. Rabe E, Pannier-Fischer F, Gerlach H, Breu FX, Guggenbichler S, Zabel M, et al. Guidelines for sclerotherapy of varicose veins (ICD 10: I83.0, I83.1, I83.2, and I83.9). Dermatol Surg. 2004;30:687–93.

    CAS  PubMed  Google Scholar 

  11. Breu FX, Guggenbichler S, Wollmann JC. European Consensus Meeting on Foam Sclerotherapy 2006, Tegernsee, Germany. Vasa. 2008;37(suppl 71):1–29.

    PubMed  Google Scholar 

  12. Breu FX, Guggenbichler S. European Consensus Meeting on Foam Sclerotherapy, April 4–6, 2003, Tegernsee, Germany. Dermatol Surg. 2004;30:709–17.

    Article  Google Scholar 

  13. Tessari L, Cavezzi A, Frullini A. Preliminary experience with a new sclerosing foam in the treatment of varicose veins. Dermatol Surg. 2001;27:58–60.

    CAS  PubMed  Google Scholar 

  14. Bergan J. Sclerotherapy: a truly minimally invasive technique. Perspect Vasc Surg Endovasc Ther. 2008;20:70–2.

    Article  Google Scholar 

  15. Perrin M, Gillet J-L. Management of recurrent varices at the popliteal fossa after surgical treatment. Phlebology. 2008;23(2):64–8.

    Article  CAS  Google Scholar 

  16. Perrin MR, Guex JJ, Ruckley CV, et al. Recurrent varices after surgery (REVAS), a consensus document. Cardiovasc Surg. 2000;8(4):233–45.

    Article  CAS  Google Scholar 

  17. Malgor RD, Labropoulos N. Pattern and types of non-saphenous vein reflux. Phlebology. 2013;28(Suppl 1):51–4.

    Article  Google Scholar 

  18. Darvall KA, Bate GR, Adam DJ, Silverman SH, Bradbury AW. Duplex ultrasound outcomes following ultrasound-guided foam sclerotherapy of symptomatic recurrent great saphenous varicose veins. Eur J Vasc Endovasc Surg. 2011;42(1):107–14.

    Article  CAS  Google Scholar 

  19. Paraskevas P. Successful ultrasound-guided foam sclerotherapy for vulval and leg varicosties secondary to ovarian vein reflux: a case study. Phlebology. 2011;26(1):29–31.

    Article  CAS  Google Scholar 

  20. Munavalli GS, Weiss RA. Complications of sclerotherapy. Semin Cutan Med Surg. 2007;26:22–8.

    Article  CAS  Google Scholar 

  21. Goldman MP, Sadick NS, Weiss RA. Cutaneous necrosis, telangiectatic matting, and hyperpigmentation following sclerotherapy: etiology, prevention, and treatment. Dermatol Surg. 1995;21:19–29.

    Article  CAS  Google Scholar 

  22. Guex JJ. Complications and side-effects of foam sclerotherapy. Phlebology. 2009;24:270–4.

    Article  Google Scholar 

  23. Bergan JJ, Weiss RA, Goldman MP. Extensive tissue necrosis following high-concentration sclerotherapy for varicose veins. Dermatol Surg. 2000;26:535–41.

    Article  CAS  Google Scholar 

  24. Ceulen RP, Sommer A, Vernooy K. Microembolism during foam sclerotherapy of varicose veins. N Engl J Med. 2008;358:1525–6.

    Article  CAS  Google Scholar 

  25. Hobbs JT. The treatment of varicose veins: a random trial of injection- compression therapy versus surgery. Br J Surg. 1968;55:777–80.

    Article  CAS  Google Scholar 

  26. Chant AD, Jones HO, Weddell JM. Varicose veins: a comparison of surgery and injection-compression sclerotherapy. Lancet. 1972;2:1188–91.

    Article  CAS  Google Scholar 

  27. Kern P, Ramelet AA, Wütschert R, Hayoz D. Compression after sclerotherapy for telangiectasias and reticular leg veins: a randomized controlled study. J Vasc Surg. 2007;45:1212–6.

    Article  Google Scholar 

  28. Goldman MP. Treatment of varicose and telangiectatic leg veins: double-blind prospective comparative trial between aethoxyskerol and sotradecol. Dermatol Surg. 2002;28:52–5.

    PubMed  Google Scholar 

  29. Rabe E, Otto J, Schliephake D, Pannier F. Efficacy and safety of great saphenous vein sclerotherapy using standardised polidocanol foam (ESAF): a randomised controlled multicentre clinical trial. Eur J Vasc Endovasc Surg. 2008;35:238–45.

    Article  CAS  Google Scholar 

  30. Tisi PV, Beverley C, Rees A. Injection sclerotherapy for varicose veins. Cochrane Database Syst Rev. 2006;18(4):CD001732.

    Google Scholar 

  31. Rigby KA, Palfreyman SJ, Beverley C, Michaels JA. Surgery versus sclerotherapy for the treatment of varicose veins. Cochrane Database Syst Rev. 2004;18(4):CD004980.

    Google Scholar 

  32. Luebke T, Brunkwall J. Systematic review and meta-analysis of endovenous radiofrequency obliteration, endovenous laser therapy, and foam sclerotherapy for primary varicosis. J Cadiovasc Surg. 2008;49:213–33.

    CAS  Google Scholar 

  33. Wang JC, Li Y, Li GY, Xiao Y, Li WM, Ma Q, Liu JL, Lu SY. A comparison of concomitant tributary laser ablation and foam sclerotherapy in patients undergoing truncal endovenous laser ablation for lower limb varicose veins. J Vasc Interv Radiol. 2018;29(6):781–9. https://doi.org/10.1016/j.jvir.2018.01.774. [Epub ahead of print].

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer Nature Singapore Pte Ltd.

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Grover, T. (2018). Sclerotherapy for Varicose Veins. In: Khanna, A., Jindal, R. (eds) Venous Disorders. Springer, Singapore. https://doi.org/10.1007/978-981-13-1108-6_6

Download citation

  • DOI: https://doi.org/10.1007/978-981-13-1108-6_6

  • Published:

  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-13-1107-9

  • Online ISBN: 978-981-13-1108-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics