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Psycho-gastroenterology

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Functional Dyspepsia

Abstract

Epidemiological studies have indicated that there is a convincing association between psychological disorders, particularly anxiety and depression, and functional dyspepsia. Bidirectional gut–brain signals are processed by homeostatic–interoceptive brain regions in humans, and these areas show abnormalities in patients with functional dyspepsia. The evidence warrants use of a biopsychosocial model for the research and treatment of patients with functional dyspepsia. Some types of antidepressants are effective for improving symptoms and quality of life. However, these agents should be cautiously used in patients with comorbid psychological conditions due to their high rates of adverse effects. Psychological interventions in patients with functional dyspepsia remain under-researched, but cognitive behavioral therapy may ameliorate distress due to symptoms and improve health-related quality of life in some refractory patients. Understanding of the neurogastroenterological mechanism will help to elucidate the association between psychological disorders and functional dyspepsia.

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Author information

Authors and Affiliations

  1. Psychosomatic Medicine, Tohoku University Hospital, Sendai City, Miyagi, Japan

    Tomotaka Shoji, Yuka Endo & Shin Fukudo

  2. Behavioral Medicine, Graduated School of Medicine, Tohoku University, Sendai City, Miyagi, Japan

    Shin Fukudo

Authors
  1. Tomotaka Shoji
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  2. Yuka Endo
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  3. Shin Fukudo
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Corresponding author

Correspondence to Tomotaka Shoji .

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Editors and Affiliations

  1. Premier Developmental Research of Medicine, Osaka Medical College, Takatsuki, Osaka, Japan

    Kazunari Tominaga

  2. Department of General Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan

    Hiroaki Kusunoki

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Shoji, T., Endo, Y., Fukudo, S. (2018). Psycho-gastroenterology. In: Tominaga, K., Kusunoki, H. (eds) Functional Dyspepsia. Springer, Singapore. https://doi.org/10.1007/978-981-13-1074-4_9

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  • DOI: https://doi.org/10.1007/978-981-13-1074-4_9

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  • Online ISBN: 978-981-13-1074-4

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