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Graphene-Based Nanocomposites as Promising Options for Hard Tissue Regeneration

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Cutting-Edge Enabling Technologies for Regenerative Medicine

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1078))

Abstract

Tissues are often damaged by physical trauma, infection or tumors. A slight injury heals naturally through the normal healing process, while severe injury causes serious health implications. Therefore, many efforts have been devoted to treat and repair various tissue defects. Recently, tissue engineering approaches have attracted a rapidly growing interest in biomedical fields to promote and enhance healing and regeneration of large-scale tissue defects. On the other hand, with the recent advances in nanoscience and nanotechnology, various nanomaterials have been suggested as novel biomaterials. Graphene, a two-dimensional atomic layer of graphite, and its derivatives have recently been found to possess promoting effects on various types of cells. In addition, their unique properties, such as outstanding mechanical and biological properties, allow them to be a promising option for hard tissue regeneration. Herein, we summarized recent research advances in graphene-based nanocomposites for hard tissue regeneration, and highlighted their promising potentials in biomedical and tissue engineering.

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Acknowledgments

This work was supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI) funded by the Ministry of Health & Welfare, South Korea (HI17C1662), by the Bio & Medical Technology Development Program of the National Research Foundation (NRF) & funded by the Korean government (MSIP&MOHW) (2017M3A9E4048170), and by Basic Science Research Program through the NRF of Korea funded by the Ministry of Education (2016R1D1A1B03931076).

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Authors and Affiliations

  1. Research Center for Energy Convergence Technology, Pusan National University, Busan, South Korea

    Yong Cheol Shin

  2. Department of Cogno-Mechatronics Engineering, College of Nanoscience & Nanotechnology, Pusan National University, Busan, South Korea

    Su-Jin Song, Suck Won Hong & Dong-Wook Han

  3. GS Medical Co., Ltd., Cheongju-si, Chungcheongbuk-do, South Korea

    Seung Jo Jeong

  4. Dental Life Science Research Institute & Clinical Translational Research Center for Dental Science, Seoul National University Dental Hospital, Seoul, South Korea

    Bongju Kim

  5. Department of Dental Materials, School of Dentistry, Kyung Hee University, Seoul, South Korea

    Il Keun Kwon

  6. Department of Nanoenergy Engineering, College of Nanoscience & Nanotechnology, Pusan National University, Busan, South Korea

    Jin-Woo Oh

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  1. Yong Cheol Shin
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  2. Su-Jin Song
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  7. Jin-Woo Oh
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  8. Dong-Wook Han
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Correspondence to Dong-Wook Han .

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Editors and Affiliations

  1. The Catholic University of Korea, Seoul, Korea (Republic of)

    Heung Jae Chun

  2. Hallym University, Gangwon-do, Korea (Republic of)

    Chan Hum Park

  3. Kyung Hee University, Seoul, Korea (Republic of)

    Il Keun Kwon

  4. Chonbuk National University, Jeonju, Korea (Republic of)

    Gilson Khang

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Shin, Y.C. et al. (2018). Graphene-Based Nanocomposites as Promising Options for Hard Tissue Regeneration. In: Chun, H., Park, C., Kwon, I., Khang, G. (eds) Cutting-Edge Enabling Technologies for Regenerative Medicine. Advances in Experimental Medicine and Biology, vol 1078. Springer, Singapore. https://doi.org/10.1007/978-981-13-0950-2_6

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