Chitosan-Based Dressing Materials for Problematic Wound Management

  • Ji-Ung Park
  • Eun-Ho Song
  • Seol-Ha Jeong
  • Juha Song
  • Hyoun-Ee KimEmail author
  • Sukwha KimEmail author
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1077)


Wound healing is a complex mechanism involving a variety of factors and is a representative process of tissue growth and regeneration in our body. Surface-based interactions between the dressing material and the wound may significantly influence the healing phase. Advances in understanding the mechanism of wound healing have led to the development of numerous dressing materials that can accelerate the healing process. However, these materials have a passive role in wound healing. It is therefore necessary to develop novel wound dressing materials, especially effective for clinically problematic wounds. Chitosan-based dressing materials are considered suitable for clinically problematic wounds as they exhibit several characteristic features, such as facilitating hemostasis, enhanced wound healing during the inflammatory and proliferative phases, antimicrobial effect, etc. Here, we review the current status of clinically available dressing materials and studies on the biological characteristics of chitosan, and discuss the potential applications of chitosan in multi-functional dressing materials for accelarated wound healing.


Wound healing Dressing materials Chitosan 


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Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  1. 1.Department of Plastic and Reconstructive SurgerySeoul National University Boramae HospitalSeoulSouth Korea
  2. 2.Department of Materials Science and EngineeringSeoul National UniversitySeoulSouth Korea
  3. 3.School of Chemical and Biomedical EngineeringNanyang Technological UniversitySingaporeSingapore
  4. 4.Biomedical Implant Convergence Research Center, Advanced Institutes of Convergence TechnologySuwonSouth Korea
  5. 5.Department of Plastic and Reconstructive SurgerySeoul National University College of MedicineSeoulSouth Korea

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