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Recent Trends in Hydroxyapatite (HA) Synthesis and the Synthesis Report of Nanostructure HA by Hydrothermal Reaction

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Novel Biomaterials for Regenerative Medicine

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1077))

Abstract

This research summary the trend in synthesis of Hydroxyapatite (HA) using different route such as dry method and wet method (co-precipitation method; emulsion method, hydrolysis method, sol-gel method, hydrothermal method). In addition, the research group also report the technique to synthesis nano-structure HA by hydrothermal reaction using Ca(OH)2 and H3PO4 with the Ca/P molar ratio of 1.67. The mixture after homogenized for 2 h, follow by hydrothermal reaction at different hydrothermal temperature time (100 °C, 150 °C, and 180 °C) and different hydrothermal reaction time (0 h, 12 h and 24 h). The 180 °C-hydrothermal treated-HA has needle-like shape with the diameter of 10 ~ 20 nm and length of below 100 nm, which is similar with human bone. For the hydrothermal reaction, temperature is the key to form nanostructure HA.

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Acknowledgement

This research is funded by Vietnam National University Ho Chi Minh City (VNU-HCM) under grant number B2015-20a-01. Some of the material characterization facility is supported by National key lab for Polymer and Composite Materials-HCMUT, VAST and HUFI.

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Authors and Affiliations

  1. Faculty of Materials Technology, Ho Chi Minh City University of Technology (HCMUT), Vietnam National University (VNU-HCM), Ho Chi Minh City, Vietnam

    Pham Trung Kien, Huynh Dai Phu & Nguyen Vu Viet Linh

  2. National Key Lab for Polymer and Composite Materials, HCMUT, Ho Chi Minh City, Vietnam

    Huynh Dai Phu & Nguyen Vu Viet Linh

  3. Graduate School of Science and Technology, Department of Pharmacy and Medicine, Vietnam Academy of Science and Technology, Ho Chi Minh City, Vietnam

    Tran Ngoc Quyen

  4. Key Lab for Materials Technology, Ho Chi Minh City University of Technology, Ho Chi Minh City, Vietnam

    Nguyen Thai Hoa

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  1. Pham Trung Kien
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  3. Nguyen Vu Viet Linh
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  4. Tran Ngoc Quyen
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Correspondence to Pham Trung Kien .

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Editors and Affiliations

  1. The Catholic University of Korea, Seoul, Korea (Republic of)

    Heung Jae Chun

  2. Korea Institute of Science and Technology, Seoul, Korea (Republic of)

    Kwideok Park

  3. Korea Institute of Radiological and Medical Sciences, Seoul, Korea (Republic of)

    Chun-Ho Kim

  4. Chonbuk National University, Jeonju, Korea (Republic of)

    Gilson Khang

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Kien, P.T., Phu, H.D., Linh, N.V.V., Quyen, T.N., Hoa, N.T. (2018). Recent Trends in Hydroxyapatite (HA) Synthesis and the Synthesis Report of Nanostructure HA by Hydrothermal Reaction. In: Chun, H., Park, K., Kim, CH., Khang, G. (eds) Novel Biomaterials for Regenerative Medicine. Advances in Experimental Medicine and Biology, vol 1077. Springer, Singapore. https://doi.org/10.1007/978-981-13-0947-2_18

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