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Fabrication of Hydrogel Materials for Biomedical Applications

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Novel Biomaterials for Regenerative Medicine

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1077))

Abstract

Hydrogels are three-dimensional hydrophilic polymeric networks that can be made from a wide range of natural and synthetic polymers. This review discusses recent advanced engineering methods to fabricate hydrogels for biomedical applications with emphasis in cardiac constructs and wound healing. Layer-by-Layer (LbL) assembly offers a tissue-engineered construct with robust and highly ordered structures for cell proliferation and differentiation. Three-dimensional printings, including inkjet printing, fused deposition modeling, and stereolithographic apparatus, have been widely employed to fabricate complex structures (e.g., heart valves). Moreover, the state-of-the-art design of intelligent/stimulus-responsive hydrogels can be used for a wide range of biomedical applications, including drug delivery, glucose delivery, shape memory, wound dressings, and so on. In the future, an increasing number of hydrogels with tunable mechanical properties and versatile functions will be developed for biomedical applications by employing advanced engineering techniques with novel material design.

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Author notes

  1. Authors Jen Ming Yang and Olajire Samson Olanrele have been equally contributed to this chapter.

Authors and Affiliations

  1. Department of Chemical and Materials Engineering, Chang Gung University, TaoYuan, Taiwan, Republic of China

    Jen Ming Yang

  2. Department of General Dentistry, Chang Gung Memorial Hospital, TaoYuan, Taiwan, Republic of China

    Jen Ming Yang

  3. Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan, Republic of China

    Jen Ming Yang

  4. Institute of Metal Research, Chinese Academy of Sciences, Shenyang, Liaoning, People’s Republic of China

    Olajire Samson Olanrele & Xing Zhang

  5. School of Materials Science and Engineering, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China

    Olajire Samson Olanrele & Xing Zhang

  6. Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan, Republic of China

    Chih Chin Hsu

  7. School of Traditional Chinese Medicine, Chang Gung University, Taoyuan, Taiwan, Republic of China

    Chih Chin Hsu

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  1. Jen Ming Yang
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Correspondence to Jen Ming Yang or Xing Zhang .

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  1. The Catholic University of Korea, Seoul, Korea (Republic of)

    Heung Jae Chun

  2. Korea Institute of Science and Technology, Seoul, Korea (Republic of)

    Kwideok Park

  3. Korea Institute of Radiological and Medical Sciences, Seoul, Korea (Republic of)

    Chun-Ho Kim

  4. Chonbuk National University, Jeonju, Korea (Republic of)

    Gilson Khang

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Yang, J.M., Olanrele, O.S., Zhang, X., Hsu, C.C. (2018). Fabrication of Hydrogel Materials for Biomedical Applications. In: Chun, H., Park, K., Kim, CH., Khang, G. (eds) Novel Biomaterials for Regenerative Medicine. Advances in Experimental Medicine and Biology, vol 1077. Springer, Singapore. https://doi.org/10.1007/978-981-13-0947-2_12

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