Introduction

Abstract

This book will expand on the content provided in the First Edition (Development of Antibody-Based Therapeutics: Translational Considerations, 1st Edition, 2012). Although the first publication provided a comprehensive review of the critical topics relevant for development of antibody-based therapeutics, this Second Edition will provide in-depth coverage of the key topics related to development of targeted therapeutics with key focus on the recent developments in the field. Recent advances span development of targeted modalities in exciting therapeutic areas such as immuno-oncology (IO) and application of combination therapies, novel technologies, and advances in therapeutic application of antibody-drug conjugates. We hope that this collection has successfully captured new advances relevant to the development of targeted therapeutics and will provide interested reader with an advanced knowledge of the field.

“Life is like riding a bicycle. To keep your balance you must keep moving.”

—Albert Einstein