Influence of Biomimetic Materials on Cell Migration

  • Min Sung Kim
  • Mi Hee Lee
  • Byeong-Ju Kwon
  • Min-Ah Koo
  • Gyeung Mi Seon
  • Dohyun Kim
  • Seung Hee Hong
  • Jong-Chul ParkEmail author
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1064)


In recent tissue engineering applications, the advance of biomaterials has focused on the devising of biomimetic materials that are directing new tissue formation and capable of causing specific cellular responses. These advances can be controlled by modifying the devising parameters of the materials. The biomimetic materials potentially mimic many roles of ECM in tissues. For the homogeneous distribution and biocompatibility of scaffolds by cell migration with biomimetic materials, cell migration is studied because it has a important role in physiological phenomenon and in pathologies; cancer metastasis, immune response or embryonic development. This review discusses the migration of cells with biomimetic materials for tissue engineering. It is also summarized that the recent advances of cell migration with biomimetic materials in 2-D and 3-D for tissue engineering.


Cell migration Biomimetic material Tissue engineering Extracellular matrix Scaffold 



This research was supported by the Bio & Medical Technology Development Program of theNRF funded by the Korean government, MSIP (2017M3A9B3063638).


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Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Min Sung Kim
    • 1
    • 2
  • Mi Hee Lee
    • 1
  • Byeong-Ju Kwon
    • 1
  • Min-Ah Koo
    • 1
    • 2
  • Gyeung Mi Seon
    • 1
    • 2
  • Dohyun Kim
    • 1
  • Seung Hee Hong
    • 1
    • 2
  • Jong-Chul Park
    • 1
    • 2
    Email author
  1. 1.Cellbiocontrol Laboratory, Department of Medical EngineeringYonsei University College of MedicineSeoulSouth Korea
  2. 2.Brain Korea 21 Plus Project for Medical ScienceYonsei University College of MedicineSeoulSouth Korea

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