Skip to main content

Abstract

Nardostachys jatamansi DC. is an important plant of the family Valerianaceae. Indian spikenard is the common name of the plant and is found in Himalayas. N. jatamansi is a perennial herb. The rhizomes occur in short pieces and have dark-grey colour and typical smell. Leaves are sessile and ovate. Flowers are dark pink in colour.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Ahmad M, Yousuf S, Badruzzaman Khan M, Hoda MN, Ahmad AS, Ansari MA, Ishrat T, Agarwal AK, Islam F. Attenuation by Nardostachys jatamansi of 6-hydroxydopamine-induced parkinsonism in rats: behavioral, neurochemical, and immunohistochemical studies. Pharmacol Biochem Behav. 2006;83:150–60.

    Article  CAS  PubMed  Google Scholar 

  • Arora RB, Arora CK. Hypotensive and tranquillizing activity of jatamansone (valeranone). Pharmacol Orient Plants (Academic Press, London/New York) 1963;7:51–60.

    Google Scholar 

  • Arora RB, Singh M, Arora CK. Tranquillizing activity of jatamansone. Life Sci. 1962;6:225.

    Article  Google Scholar 

  • Bagchi A, Oshima Y, Hikino H. Spirojatomol, a new skeletal sesquiterpenoid of Nardostachys jatamansi roots. Tetrahedron. 1990;46:1523–30.

    Article  CAS  Google Scholar 

  • Bagchi A, Oshima Y, Hikino H. Jatamols A and B: sesquiterpenoids of Nardostachys jatamansi roots. Planta Med. 1991;57:282–3.

    Article  CAS  PubMed  Google Scholar 

  • Biswas K. Pharmacology of Jatamansin. Active substance of the plant Nardostachys jatamansi. Prensa Med Argent. 1963;50:1021–5.

    PubMed  CAS  Google Scholar 

  • Chatterjee B, Basak U, Datta J, Banerji A, Neuman TP. Studies on the chemical constituents of Nardostachys jatamansi DC (Valerianaceae). ChemInform. 2005a;36:17.

    Google Scholar 

  • Chatterjee A, Basaka B, Dattab U, Banerji J, Neumanc A. Prangé. T. Studies on the chemical constituents of Nardostachys jatamansi. Indian J Chem. 2005b;44B:430–3.

    CAS  Google Scholar 

  • Gupta PD, Vermani V. Clinical trial of jatamansone (syn: Valeranone) in hyperkinetic behaviour disorders. Neurol India. 1968;6:168–73.

    Google Scholar 

  • Harigaya Y, Chatterjee A, Basak B, Saha M, Dutta U, Mukhopadhyay C, Banerji J, Konda Y. Structure and stereochemistry of nardostachysin, a new terpenoid ester constituent of the rhizomes of Nardostachys jatamansi. J Nat Prod. 2000;63:531–1533.

    Article  CAS  Google Scholar 

  • Joshi H, Parle M. Nardostachys jatamansi improves learning and memory in mice. J Med Food. 2006;9:113–8.

    Article  PubMed  Google Scholar 

  • Prabhu V, Karanth KS, Rao A. Effects of Nardostachys jatamansi on biogenic-amines and inhibitory amino-acids in the rat-brain. Planta Med. 1994;60:114–7.

    Article  CAS  PubMed  Google Scholar 

  • Rao VS, Rao A, Karanth KS. Anticonvulsant and neurotoxicity profile of Nardostachys jatamansi in rats. J Ethnopharmacol. 2005;102:351–6.

    Article  PubMed  Google Scholar 

  • Rücker G, Tautges J. The structure of jatamansic acid. Arch Pharm (Weinheim). 1974;307:791–5.

    Article  Google Scholar 

  • Rucker G, Tautges J, Sieck A, Wenzl H, Graf E. Nardostachys jatamansi: a chemical, pharmacological and clinical appraisal. Indian Med Res. 1978a;28:17.

    Google Scholar 

  • Rucker G, Tautges J, Sleck A, Wenzl H, Graf E. Isolation and pharmacological activity of the sesquiterpene valeranone from Nardostachys jatamansi DC (in German). Arzneimittelforschung. 1978b;28:7–13.

    PubMed  CAS  Google Scholar 

  • Salim S, Ahmad M, Zafar KS, Ahmad AS, Islam F. Protective effect of Nardostachys jatamansi in rat cerebral ischemia. Pharmacol Biochem Behav. 2003;74:481–6.

    Article  CAS  PubMed  Google Scholar 

  • Sastry SD, Maheswari ML, Chakravarti KK, Bhattacharyya SC. Terpenoids – CVI: the structure of calarenol. Tetrahedron. 1967;23:1997–2000.

    Article  CAS  Google Scholar 

  • Vinutha JP. Acetyl cholinesterase inhibitory activity of methanolic and successive water extracts of Nardostachys jatamansi. Indian J Pharmacol. 2007;23:127–31.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer Nature Singapore Pte Ltd.

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Saroya, A.S., Singh, J. (2018). Neuropharmacology of Nardostachys jatamansi DC.. In: Pharmacotherapeutic Potential of Natural Products in Neurological Disorders. Springer, Singapore. https://doi.org/10.1007/978-981-13-0289-3_17

Download citation

Publish with us

Policies and ethics