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Nanotoxicology in Caenorhabditis elegans pp 205–226Cite as

Confirmation of Nanomaterials with Low-Toxicity or Non-toxicity Property

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Abstract

In the nanoscience field, besides the preparation of engineered nanomaterials (ENMs) with excellent physicochemical properties, to obtain the ENMs with the safe property for environmental organisms and human beings is also another important aim. In this chapter, we summarize the progress on the assessment and confirmation of low-toxicity or relative non-toxicity property of some important ENMs (such as graphite, graphene quantum dots (GQDs), carboxyl-functionalized graphene (G–COOH), Gd@C82(OH)22, fluorescent nanodiamond (FND), halloysite clay nanotubes (HNTs), and titanium dioxide nanoparticles (TiO2-NPs)) using Caenorhabditis elegans. With the TiO2-NPs as an example, the relative safe property of TiO2-NPs at realistic concentrations was further discussed. Moreover, the recovery response of toxicity of TiO2-NPs after transfer to the normal conditions and the underlying mechanisms in nematodes were also introduced.

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  1. Medical School, Southeast University, Nanjing, Jiangsu, China

    Dayong Wang

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Wang, D. (2018). Confirmation of Nanomaterials with Low-Toxicity or Non-toxicity Property. In: Nanotoxicology in Caenorhabditis elegans. Springer, Singapore. https://doi.org/10.1007/978-981-13-0233-6_9

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