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Scope of Pathogenesis-Related Proteins Produced by Plants in Interrupting Quorum Sensing Signaling

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Book cover Biotechnological Applications of Quorum Sensing Inhibitors

Abstract

Quorum sensing (QS) is a microbial consortia growth gene regulation process mediated by hormone like signaling molecules known as auto inducers (AI). QS is involved in regulating virulent factors of pathogens that is required for the successful establishment of bacterial infections. Therefore, interrupting the QS signaling process can be exploited as an effective strategy for antimicrobial therapy. Plants produce several compounds like pathogenesis-related proteins as a result of pathogen exposure and stress factors that might affect the quorum sensing signaling process. Plant-pathogen interactions during pathogenic attack leads to the production of secondary metabolites, which in turn can target the bacterial QS system by either inhibiting synthesis of signal transducers, degrading the transducers and/or receptor targeting mechanism. Since plants are safe for human consumption, their usage is considered as a safer alternative to the conventional antibiotic mediated approach to treat infections.

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Correspondence to Pachaiappan Raman .

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Chinnappan, P., Rajan, S., Thondanure, S., Champalal, L., Raman, P. (2018). Scope of Pathogenesis-Related Proteins Produced by Plants in Interrupting Quorum Sensing Signaling. In: Kalia, V. (eds) Biotechnological Applications of Quorum Sensing Inhibitors. Springer, Singapore. https://doi.org/10.1007/978-981-10-9026-4_18

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