Abstract
Volumetric Modulated Arc Therapy (VMAT) uses non-uniform intensity fields allowing volumetric complex dose distributions. The simultaneous MultiLeaf Collimator (MLC) motion and Gantry rotation pose difficulties in the dose distribution calculation by Treatment Planning Systems (TPS). Furthermore, a dedicated Quality Assurance (QA) program and patient-specific dose verifications are requested. Monte Carlo dose calculation in Radiotherapy (RT) is a gold standard due to its most detailed description of radiation-matter interaction. Recently, the PRIMO software was proposed, providing several built-in RT units models, including TrueBeam. Nevertheless, VMAT is not implemented yet. In this work, TrueBeam was simulated in PRIMO using 6 and 10 MV in Flatness Filter Free (FFF) mode and at 15 MV with Flatness Filter inserted. The results were validated by Gamma Function (2%, 2 mm) based on reference measurements in water tank. The VMAT complex dynamic delivery is divided into a customizable number of probabilistically sampled static configurations of jaws, leaves and gantry angles. In-house algorithms were developed to interpolate the LINAC geometrical information along the process once the planned information is retrieved from the TPS output DICOM file. A Graphical User Interface (GUI) was developed to assist the user to configure PRIMO to simulate complex deliveries. Static simulations in reference conditions showed always >97% of Gamma points <1 for PDD and profiles at various depths and fields sizes for the 6, 10 and 15 MV primary beam respectively. The GUI properly read, manipulated and wrote the configuration data in a “ppj” format, which was accepted by PRIMO. The dynamic jaws, MLC and gantry motion were positively assessed by visual inspection of the static beam configuration in PRIMO. Dynamic irradiations were simulated and the gamma function tests against reference dose distributions showed good agreement with typical QA criteria. A GUI to configure PRIMO for VMAT irradiations allowed to enable a flexible workflow for simulating a general dynamic treatment.
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References
K. Otto, “Volumetric modulated arc therapy: Imrt in a single gantry arc,” Med. Phys., no. 35, pp. 310–317, 2008.
P. Andersson, M. Krantz, R. Chakarova, and R. Cronholm, “Monte carlo patient specific pre- treatment qa system for volumetric modulated arc therapy,” Swedish Radiation Safety Authority, 2017.
F. Verhaegen and J. Seco, Monte Carlo Techniques in Radiation Therapy. CRC Press.
A. Lallena, L. Brualla, and M. Rodriguez, “Monte carlo systems used for treatment planning and dose verification,” Strahlenther. Onkol., 2016.
J. Sempau, M. Rodriguez, and L. Brualla, “Primo: A graphical environment for the monte carlo simulation of varian and elekta linacs,” Strahlenther. Onkol., no. 1889, pp. 881–886, 2013.
M. F. Belosi et. al, “Monte carlo simulation of truebeam flattening-filter-free beams using varian phase-space files: Comparison with experimental data,” Med. Phys., no. 41, 2014.
Shih and R.e.a., “Dynamic wedge versus physical wedges: A monte carlo study,” Med. Phys., no. 28, pp. 612–619, 2001.
F. Verhaegen et al., “A method of simulating dynamic multileaf collimators using monte carlo techniques for intensity-modulated radiation therapy.,” Phys. Med. Biol., no. 46, pp. 2283–2298, 2001.
A. Esposito et al., “PRIMO Software as a tool for Monte Carlo Simulations of Intensity Modulated Radiotherapy: A Feasibility study,” Phys. Med., vol. 32, no. 3, p. 205, 2016.
C.-M. Ma et al., “Phase-space database for external beam radiotherapy,” IAEA - International Atomic Energy Agency, Technical report, 2005.
J. Sempau, L. Brualla, and M. Rodriguez, PRIMO User’s Manual - SOFTWARE VERSION 0.1.5.1202.
Acknowledgements
This article is a result of the project NORTE-01-0145-FEDER-000027, supported by Norte Portugal Regional Operational Programme (NORTE 2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF).
The author J. Oliveira acknowledges the research grant CI-IPOP-BIFMRPR2018/UID/DTP/00776/POCI-01-0145-FDER-006868.
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Oliveira, J., Esposito, A., Santos, J. (2019). Configuration of Volumetric Arc Radiotherapy Simulations Using PRIMO Software: A Feasibility Study. In: Lhotska, L., Sukupova, L., Lacković, I., Ibbott, G. (eds) World Congress on Medical Physics and Biomedical Engineering 2018. IFMBE Proceedings, vol 68/3. Springer, Singapore. https://doi.org/10.1007/978-981-10-9023-3_90
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DOI: https://doi.org/10.1007/978-981-10-9023-3_90
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