Abstract
Infrared neural stimulation (INS) gains growing interest both in electrophysiological research and for potential clinical applications, promising advantages like contactless operation, superior focality and hence spatial selectivity, and lack of electrical stimulation artifacts for nerve stimulation. We established an experimental setup for systematic investigation of relevant INS parameters, since little quantitative research for deeper understanding has been performed yet. Our customized setup facilitates the use of multiple fiber-based infrared laser systems of different wavelengths for remote stimulation, multi-site low-noise EMG recording and automated laser beam characterization. Hence, this setup simplifies upcoming systematic studies on both technical and physiological conditions for laser-induced neural activation. Determination of safe margins for reliable stimulation will help to understand the underlying physiological mechanisms and establish INS as alternative method for neural activation. Here, we present our experimental setup and preliminary results of our ongoing work.
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The authors declare that they have no conflict of interests. This work was funded by the German Federal Ministry of Education and Research (BMBF), project NeuroPhos, FKZ 13GW0155C.
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Schlett, P., Wegner, C., Krueger, T., Buckert, T., Klotzbuecher, T., Hofmann, U.G. (2019). Experimental Setup for the Systematic Investigation of Infrared Neural Stimulation (INS). In: Lhotska, L., Sukupova, L., Lacković, I., Ibbott, G. (eds) World Congress on Medical Physics and Biomedical Engineering 2018. IFMBE Proceedings, vol 68/3. Springer, Singapore. https://doi.org/10.1007/978-981-10-9023-3_14
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DOI: https://doi.org/10.1007/978-981-10-9023-3_14
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