Abstract
Reward prediction is essential for learning behavior and decision-making process in the brain. It is well known that the neurons in both prefrontal cortex (PFC) and striatum are involved in encoding reward information and the interplay between the PFC and striatum plays an important role in cognitive processes. However, it remains elusive how interaction between PFC and striatum is modulated in reward conditions. To investigate this issue, the local field potentials (LFPs) were simultaneously recorded in the lateral PFC and striatum of a male monkey while performing the sequential paired-association task with the asymmetric reward scheme. The nonlinear interdependence (NLI), a measure of the generalized synchrony characterizing both the coupling strength and the coupling direction, was used to quantify the strength of bidirectional functional connectivity between the PFC and striatum. The results suggest that PFC has strong bi-directional coupling with the striatum and the interaction in beta frequency band plays an important role in regulating monkey’s behavior in reward prediction task.
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Alexander, G., DeLong, M., Strick, P.: Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu. Rev. Neurosci. 9, 357–381 (1986)
Asaad, W., Eskandard, E.: Encoding of both positive and negative reward prediction errors by neurons of the primate lateral prefrontal cortex and caudate nucleus. J. Neurosci. 31, 17772–17787 (2011)
Deserno, L., Huys, Q., Boehme, R., Buchert, R., Heinze, H.: Ventral striatal dopamine reflects behavioral and neural signatures of model- based control during sequential decision making. Proc. Natl. Acad. Sci. U. S. A. 112, 1595–1600 (2015)
Hikosaka, O., Isoda, M.: Switching from automatic to controlled behavior: cortico-basal ganglia mechanisms. Trends Cogn. Sci. 14, 154–161 (2010)
Yoon, J.H., Minzenberg, M.J., Raouf, S., D’Esposito, M., Carter, C.S.: Impaired prefrontal-basal ganglia functional connectivity and substantia nigra hyperactivity in schizophrenia. Biol. Psychiatry. 74, 122–129 (2013)
Antzoulatos, E., Miller, E.: Increases in functional connectivity between prefrontal cortex and striatum during category learning. Neuron. 83, 216–225 (2014)
Pan, X., Sawa, K., Tsuda, I., Tsukada, M., Sakagami, M.: Reward prediction based on stimulus categorization in primate lateral prefrontal cortex. Nat. Neurosci. 11, 703–712 (2008)
Miller, E.K., Buschman, T.J.: Cortical circuits for the control of attention. Curr. Opin. Neurobiol. 23, 216–222 (2013)
Liang, Z., Ren, Y., Yan, J.: A comparison of different synchronization measures in electroencephalogram during propofol anesthesia. J. Clin. Monit. Comput. 30, 451–466 (2016)
Quian-Quiroga, R., Kraskov, A., Kreuz, T., Grassberger, P.: Performance of different synchronization measures in real data: a case study on electroencephalographic signals. Phys. Rev. 65, 1–14 (2002)
Chen, D., Li, X., Cui, D., Wang, L., Lu, D.: Global synchronization measurement of multivariate neural signals with massively parallel nonlinear interdependence analysis. IEEE Trans. Neural Syst. Rehabil. Eng. 22, 33–43 (2014)
Pei-Chen, L., Chih-Hao, C.: Spatially nonlinear interdependence of alpha-oscillatory neural networks under chan meditation. Evid. Based Complement. Alternat. Med. 360371: 1–12 (2013)
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This work was supported in part by the National Natural Science Foundation of China under Grant No. 61075070 and Key Grant No. 11232005.
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Wen, Z., Zhang, J., Pan, X., Wang, R. (2018). Quantitative Analysis of Functional Connectivity Between Prefrontal Cortex and Striatum in Monkey. In: Delgado-García, J., Pan, X., Sánchez-Campusano, R., Wang, R. (eds) Advances in Cognitive Neurodynamics (VI). Advances in Cognitive Neurodynamics. Springer, Singapore. https://doi.org/10.1007/978-981-10-8854-4_44
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DOI: https://doi.org/10.1007/978-981-10-8854-4_44
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