Abstract
The synthesis of deshydroxy skyllamycins A–C (116–118) described in the previous chapter laid the foundation for the synthesis of the native natural products, skyllamycins A–C (101–103). While a number of synthetic challenges were overcome during the synthesis of deshydroxy skyllamycins A–C (116–118), the installation of the unusual α-OH-Gly residue was not investigated. As such, before beginning the synthesis of skyllamycins A–C (101–103) previous methods for investigating the installation of the unusual α-OH-Gly motif were reviewed.
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Giltrap, A. (2018). Total Synthesis of Skyllamycins A–C. In: Total Synthesis of Natural Products with Antimicrobial Activity. Springer Theses. Springer, Singapore. https://doi.org/10.1007/978-981-10-8806-3_4
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DOI: https://doi.org/10.1007/978-981-10-8806-3_4
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