Abstract
A number of studies have been carried out to establish the anti-epileptic activity of N. sativa. Thymoquinone (TQ) is found in volatile oil of the plant and is considered the main constituent responsible for its anti-epileptic effect. Mechanism of action of TQ on seizures is not completely established; however some researchers believe that it produces anticonvulsant effect by interacting with gamma-aminobutyric acid (GABA). Some researchers in their study found that the co-administration of TQ and some known anti-epileptic drugs led to the potentiation of their anti-epileptic effect and suppressed their adverse effects.
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Khalilullah, H. (2018). Anti-epileptic Action of Thymoquinone. In: Younus, H. (eds) Molecular and Therapeutic actions of Thymoquinone. Springer, Singapore. https://doi.org/10.1007/978-981-10-8800-1_7
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DOI: https://doi.org/10.1007/978-981-10-8800-1_7
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