Oxidative Modification of Trichocyte Keratins

  • Jolon M. DyerEmail author
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1054)


Oxidation of keratin results in a range of deleterious effects, including discolouration and compromised physical and mechanical properties. Keratin oxidative degradation is driven by molecular-level events, with accumulation of modifications at the protein primary level resulting directly in changes to secondary, tertiary and quaternary structure, as well as eventually changes in the observable physical and chemical properties. Advances in proteomic analysis techniques provide an increasingly clearer insight into the cascade of molecular modification underpinning keratin oxidation and how this translates through to higher order changes in properties. This chapter summarises the effects of oxidation on keratin-based materials, the types of molecular modification associated with this, and advances in techniques and approaches for characterising this modification.


Keratin Protein Oxidation Redox Modification 


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© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  1. 1.AgResearch Ltd.LincolnNew Zealand

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