To Estimate the Activity of Acid Phosphatase in Serum
The greatest activity of acid phosphatase (ACP) occurs in semen (prostate gland). ACP is lysosomal enzyme. The prostatic enzyme is found in lysosome of prostrate epithelium. Small amounts are also present in the platelets, leucocytes, liver, kidney, spleen, and pancreas. Approximately one-half of the total serum ACP activity in males is contributed from the prostate. The rest of activity is due to the liver and disintegrating platelets and erythrocytes. In females, activity is from the liver, erythrocytes, and platelets.