Skip to main content

Breviscapine

  • Chapter
  • First Online:
Natural Small Molecule Drugs from Plants
  • 229 Accesses

Abstract

Breviscapine is extracted from Erigeron breviscapus, the main component of which is scutellarin. Breviscapine has a good pharmacological activity in the treatment of cardiovascular and cerebrovascular diseases. The oral bioavailability of ordinary tablets and granules is very low; at the same time, the half-life of ordinary injection and injection powder is short, eliminating quickly in the body. Therefore, the new preparations for breviscapine such as liposomal injections, microcapsules, sublingual tablets, orally disintegrating tablets, self-emulsifying soft capsules, and other quick-release preparations are in the stage of development.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 189.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 249.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Yunnan Institute of Materia Medica. Study on the chemical components of Erigeron breviscapus. Chin Herb Med Commun. 1976;11:11–4.

    Google Scholar 

  2. Yang WY, Zhang Y. The folk application status of Erigeron breviscapus. Chin Med Newsp. 2005;5(31):A07.

    Google Scholar 

  3. Cui JM, Wu S. Advances in research on breviscapine. Nat Prod Res Dev. 2003;15(3):255–8.

    CAS  Google Scholar 

  4. Yang LM, Gu J, Lin MJ, et al. Advances in research on breviscapine. Tianjin Pharm. 2010;22(1):56–60.

    Google Scholar 

  5. Zhang XD, Liu J, Zhang WB, et al. Research advance on cardiovascular pharmacological and clinical application of breviscapine. China Pharm. 2007;16(21):3–5.

    CAS  Google Scholar 

  6. Guo C, Zhu YR, Weng Y, et al. Therapeutic time window and underlying therapeutic mechanism of breviscapine injection against cerebral ischemia/reperfusion injury in rats. J Ethnopharmacol. 2014;151(1):660–6.

    Article  CAS  Google Scholar 

  7. Zheng CJ, Ou WL, Shen HY, et al. Combined therapy of diabetic peripheral neuropathy with breviscapine and mecobalamin a systematic review and a meta-analysis of Chinese studies. Biomed Res Int. 2015;2015:680756.

    PubMed  PubMed Central  Google Scholar 

  8. Wei N. Advances of breviscapine in clinical applications and its side-effects. China Pharm. 2011;4(2):144–6.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Guan-Hua Du .

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer Nature Singapore Pte Ltd. and People's Medical Publishing House, PR of China

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Wang, DS., Yan, Y., Fang, LH., Du, GH. (2018). Breviscapine. In: Natural Small Molecule Drugs from Plants. Springer, Singapore. https://doi.org/10.1007/978-981-10-8022-7_31

Download citation

Publish with us

Policies and ethics