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Advances in the Pathology of Lung Adenocarcinoma

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Early-stage Lung Cancer

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Abstract

The major revision in the IASLC/ATS/ERS international multidisciplinary classification of lung adenocarcinoma is a categorization of both adenocarcinoma in situ (AIS) and atypical adenomatous hyperplasia (AAH) as preinvasive lesions. Practically, AIS is considered as the cornerstone and irreversible stage in the development of lung adenocarcinoma. The conceptual induction of minimally invasive adenocarcinoma (MIA) marks another significant change in the pathology of lung adenocarcinoma. Accurate recognition of AIS and differentiation from MIA are essential to the early diagnosis of lung adenocarcinoma. Radiological imaging information is more important than ever for pathologists specialized in early lung cancer. Metaphorically, if what radiological imaging reflects is the entire forest, what the pathological imaging reveals is a single tree and its leaves. With the guidance of radiological imaging, pathologists can precisely sample small-sized lung specimens and examine high-risk areas with solid components in suspicion of disease invasion.

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Author information

Authors and Affiliations

  1. Department of Pathology, Shanghai Jiaotong University, Shanghai Chest Hospital, Shanghai, China

    Na Li & Jie Zhang

  2. Department of Radiology, Fudan University Huadong Hospital, Shanghai, China

    Ming Li

Authors
  1. Na Li
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  2. Jie Zhang
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  3. Ming Li
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Editors and Affiliations

  1. Fudan University Huadong Hospital , Shanghai, China

    Xiangpeng Zheng

  2. Fudan University Huadong Hospital , Shanghai, China

    Ming Li

  3. Fudan University Huadong Hospital , Shanghai, China

    Guozhen Zhang

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© 2018 Springer Nature Singapore Pte Ltd. and People's Military Medical Press

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Li, N., Zhang, J., Li, M. (2018). Advances in the Pathology of Lung Adenocarcinoma. In: Zheng, X., Li, M., Zhang, G. (eds) Early-stage Lung Cancer. Springer, Singapore. https://doi.org/10.1007/978-981-10-7596-4_1

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  • DOI: https://doi.org/10.1007/978-981-10-7596-4_1

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-10-7595-7

  • Online ISBN: 978-981-10-7596-4

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